VIIBRE - Publications 

Letters, Communications, Brief Reports & Commentaries | Book Chapters | Method Papers & Appl.Notes
Thematic Issues

Research and Invited Review Articles

2022:

Higashi H, Yagi H, Kuroda K, Tajima K, Kojima H, Nishi K, Morisaku T, Hirukawa K, Fukuda K, Matsubara K, Kitago M, Shinoda M, Obara H, Adachi S, Nishimura K, Natsume T, Tomi M, Soto-Gutierrez A, Kitagawa Y, Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model, Am. J. Transplant., 22, 731 –  744, 2022 DOI

2021:

Singh, D, Deosarkar, S P, Cadogan, E, Flemington, V, Bray, A, Zhang, J, Reiserer, R S, Schaffer, D K, Gerken, G B, Britt, C M, Werner, E M, Gibbons, F D, Kostrzewski, T, Chambers, C E, Davies, E J, Montoya, A R, Fok, J H L, Hughes, D, Fabre, K, Wagoner, M P, Wikswo, J P, and Scott, C W. A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models. PLoS Biol.,20: e3001624. 2021. PMCID: PMC9135222  DOI

Gillette AA, Babiarz CP, VanDommelen AR, Pasch CA, Clipson L, Matkowskyj KA, Deming DA, Skala MC, Autofluorescence Imaging of Treatment Response in Neuroendocrine Tumor Organoids, Cancers (Basel), 13:1873, 2021. PMCID: PMC8070804 DOI

Datta R, Gillette A, Stefely M, Skala MC, Recent innovations in fluorescence lifetime imaging microscopy for biology and medicine, J. Biomed. Opt., 26: 070603, 2021. PMCID: PMC8271181 DOI

Haep N, Florentino RM, Squires JE, Bell A, Soto-Gutierrez A, The Inside-Out of End-Stage Liver Disease: Hepatocytes are the Keystone, Semin. Liver Dis., 41:213-224, 2021. PMC-Exempt (Review) DOI

Miller DR, Schaffer DK, Neely MD, McClain ES, Travis AR, Block III FE, McKenzie J, Werner EM, Armstrong L, Markov DA, Bowman AB, Ess KC, Cliffel DE, Wikswo JP, A bistable, multiport valve enables microformulators creating microclinical analzyers that reveal aberrant glutamate metabolism in astrocytes derived from a tuberous sclerosis patient, Sensor. Actuat. B-Chem., 341:129972, 2021, PMCID: PMC8174775 DOI

Motomura T, Amirneni S, Diaz-Aragon R, Faccioli LAP, Malizio MR, Coard MC, Kocas-Kilicarslan ZN, Frau C, Haep N, Ostrowska A, Florentino RM, Soto-Gutierrez A, Is HSD17B13 Genetic Variant a Protector for Liver Dysfunction? Future Perspective as a Potential Therapeutic Target, J. Pers. Med., 11:619, 2021.  (Review for Special Issue Personalized Medicine for Liver Disease: From Molecular Mechanisms to Potential Targeted Therapies) PMCID: PMC8304981 DOI

O’Grady BJ, Geuy MD, Kim H, Balotin KM, Allchin ER, Florian DC, Bute NN, Scott TE, Lowen GB, Fricker C, Fitzgerald M,Guelcher SA, Wikswo JP, Bellan LM, Lippmann ES, Rapid Prototyping of Cell Culture Microdevices Using Parylene-Coated 3D Prints, Lab Chip, 21:4814-4822, 2021. PMCID: PMC8717820 DOI

Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT, Lansing Taylor D, Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors, Exp. Biol. Med., 246:2420-2441,2021. PMCID: PMC8606957 DOI

Tafaleng EN, Malizio MR, Fox IJ, Soto-Gutierrez A, Synthetic human livers for modeling metabolic diseases, Curr. Opin. Gastroenterol., 37:224-230, 2021. PMCID: PMC8223234 DOI

2020:

 Aisenbrey EA, Murphy WL, Synthetic Alternatives to Matrigel, Nat. Rev. Mater., 5:539-551, 2020. PMCID: PMC7500703 DOI

Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS, Predicting Susceptibility to SARS-CoV-2 Infection Based on Structural Differences in ACE2 Across Species, FASEB J., 34:15946-15960, 2020. PMCID: PMC7675292 DOI

Brown J, Faley S, Shi Y, Hillgren K, Sawada G, Baker T, Wikswo J, Lippmann E, Advances in Blood-Brain Barrier Modeling in Microphysiological Systems Highlight Critical Differences in Opioid Transport Due to Cortisol Exposure, Fluids Barriers CNS, 17:38, 2020. PMCID: PMC7269003 DOI

Datta R, Heaster TM, Sharick JT, Gillette AA, Skala MC, Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications, J. Biomed. Opt., 25:1-43, 2020. PMCID: PMC7219965 DOI

 Favreau PF, He J, Gil DA, Deming DA, Huisken J, Skala MC, Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy, Biomed. Opt. Express, 11:2591-2606, 2020. PMCID: PMC7249841 DOI

Florentino RM, Fraunhoffer NA, Morita K, Takeishi K, Ostrowska A, Achreja A, Animasahun O, Haep N, Arazov S, Agarwal N, Collin de l’Hortet A, Guzman-Lepe J, Tafaleng EN, Mukherjee A, Troy K, Banerjee S, Paranjpe S, Michalopoulos GK, Bell A, Nagrath D, Hainer SJ, Fox IJ, Soto-Gutierrez A, Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans, Hepatol. Commun. 4:859-875, 2020. PMCID: PMC7262291 DOI

Hawkins KG, Casolaro C, Brown JA, Edwards DA, Wikswo JP, The Microbiome and the Gut-Liver-Brain Axis for CNS Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models, Clin. Pharmacol. Ther., 108:929-948, 2020. PMCID: PMC7572575 DOI

Kaushik G, Gupta K, Harms V, Torr E, Evans J, Johnson HJ, Soref C, Acevedo-Acevedo S, Antosiewicz-Bourget J, Mamott D, Uhl P, Johnson BP, Palecek SP, Beebe DJ, Thomson JA, Daly WT, Murphy WL, Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity, Adv. Healthc. Mater., 9:e2000825, 2020. PMCID: PMC8016604 DOI

 Klofas LK, Short BP, Snow JP, Sinnaeve J, Rushing GV, Westlake G, Weinstein W, Ihrie RA, Ess KC, Carson RP, DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons, Neurobiol. Dis., 143:104975, 2020. PMCID: PMC7462127 DOI

Sharick JT, Walsh CM, Sprackling CM, Pasch CA, Pham DL, Esbona K, Choudhary A, Garcia-Valera R, Burkard ME, McGregor SM, Matkowskyj KA, Parikh AA, Meszoely IM, Kelley MC, Tsai S, Deming DA, Skala MC, Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment, Front. Oncol., 10:553, 2020. PMCID: PMC7242740 DOI

Sulgin AA, Sidorova TN, Sidorov VY, Growth and Characterization of a Tissue-Engineered Construct from Human Coronary Artery Smooth Muscle Cells, Bull. Sib. Med., 19:85-95, 2020. PMCID: PMC7451258 DOI

Takeishi K, Collin de l’Hortet A, Wang Y, Handa K, Guzman-Lepe J, Matsubara K, Morita K, Jang S, Haep N, Florentino RM, Yuan F, Fukumitsu K, Tobita K, Sun W, Franks J, Delgado ER, Shapiro EM, Fraunhoffer NA, Duncan AW, Yagi H, Mashimo T, Fox IJ, Soto-Gutierrez A, Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells, Cell Rep., 31:107711, 2020. PMCID: PMC7734598 DOI

2019:

Auner AW, Tasneem KM, Markov DA, McCawley LJ, Hutson MS, Chemical-PDMS Binding Kinetics and Implications for Bioavailability in Microfluidic Devices, Lab Chip, 19:864-874, 2019  DOI

Miedel MT, Gavlock DC, Jia S, Gough A, Taylor DL, Stern AM, Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System, Sci. Rep., 9:8341, 2019. PMCID: PMC6554298 DOI

Neal EH, Marinelli NA, Shi Y, McClatchey PM, Balotin KM, Gullett DR, Hagerla KA, Bowman AB, Ess KC, Wikswo JP, Lippmann ES, A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from iPSCs, Stem Cell Reports, 12:1380-1388, 2019. PMCID: PMC6565873 DOI

Popik W, Correa H, Khatua A, Aronoff DM, Alcendor DJ, Mesangial Cells, Specialized Renal Pericytes and Cytomegalovirus Infectivity: Implications for HCMV Pathology in the Glomerular Vascular Unit and Post-Transplant Renal Disease, J. Transl. Sci., 5: 2019. PMCID: PMC6027753 DOI

Sharick JT, Jeffery JJ, Karim MR, Walsh CM, Esbona K, Cook RS, Skala MC, Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids, Neoplasia, 21:615-626, 2019. PMCID: PMC6514366 DOI

2018:

Karolak A, Markov DA, McCawley LJ, Rejniak KA, Towards Personalized Computational Oncology: From Spatial Models of Tumour Spheroids, to Organoids, to Tissues, J. R. Soc. Interface, 15:20170703, 2018. PMCID: PMC5805971 DOI

Miller DR, McClain ES, Cliffel DE, Electrochemical Microphysiometry Detects Cellular Glutamate Uptake, J. Electrochem. Soc., 165:G3120-G3124, 2018  DOI

Rogers M, Sobolik T, Schaffer DK, Samson PC, Johnson AC, Owens P, Codreanu SG, Sherrod SD, McLean JA, Wikswo JP, Richmond A, Engineered Microfluidic Bioreactor for Examining the Three-Dimensional Breast Tumor Microenvironment, Biomicrofluidics, 12:034102, 2018. PMCID: PMC5938175 DOI

2017:

Banjara M, Ghosh C, Dadas A, Mazzone P, Janigro D, Detection of Brain-Directed Autoantibodies in the Serum of Non-Small Cell Lung Cancer Patients, PLoS ONE, 12:e0181409, 2017. PMCID: PMC5528996 DOI

Cyr KJ, Avaldi OM, Wikswo JP, Circadian Hormone Control in a Human-on-a-Chip: In Vitro Biology’s Ignored Component?, Exp. Biol. Med., 242:1714-1731, 2017. https://doi.org/10.1177/1535370217732766 PMCID: PMC5832251 DOI

Ghosh C, Hossain M, Solanki J, Najm IM, Marchi N, Janigro D, Overexpression of Pregnane X and Glucocorticoid Receptors and the Regulation of Cytochrome P450 in Human Epileptic Brain Endothelial Cells, Epilepsia, 58:576-585, 2017. PMCID: PMC5386820 DOI

Matta P, Sherrod SD, Marasco CC, Moore DJ, McLean JA, Weitkamp J-H, In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4+ T Lymphocytes, J. Immunol., 199:3074-3085, 2017. PMCID: PMC5659751 DOI

Norris JL, Farrow MA, Gutierrez DB, Palmer LD, Muszynski N, Sherrod SD, Pino JC, Allen JL, Spraggins JM, Lubbock ALR, Jordan A, Burns W, Poland JC, Romer C, Manier ML, Nei Y, Prentice BM, Rose KL, Hill S, Van de Plas R, Tsui T, Braman NM, Keller MR, Rutherford SA, Lobdell N, Lopez CF, Lacy DB, McLean JA, Wikswo JP, Skaar EP, Caprioli RM, Integrated, High-Throughput, Multiomics Platform Enables Data-Driven Construction of Cellular Responses and Reveals Global Drug Mechanisms of Action, J. Proteome Res., 16:1364-1375, 2017  DOI

Roach T, Alcendor DJ, Zika Virus Infection of Cellular Components of the Blood-Retinal Barriers: Implications for Viral Associated Congenital Ocular Disease, J. Neuroinflammation, 14:43, 2017. PMCID: PMC5335843 DOI

Schroer AK, Shotwell MS, Sidorov VY, Wikswo JP, Merryman WD, I-Wire Heart-on-a-Chip II: Biomechanical Analysis of Contractile, Three-Dimensional Cardiomyocyte Tissue Constructs, Acta Biomater., 48:79-87, 2017. PMCID: PMC5235976 DOI

Sidorov VY, Samson PC, Sidorova TN, Davidson JM, Lim CC, Wikswo JP, I-Wire Heart-on-a-Chip I: Three-Dimensional Cardiac Tissue Constructs for Physiology and Pharmacology, Acta Biomater., 48:68-78, 2017. PMCID: PMC5235983 DOI

Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL, Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle, Sci. Rep., 7: Article 42296, 2017. PMCID: PMC5296733 DOI

Watson DE, Hunziker R, Wikswo JP, Fitting Tissue Chips and Microphysiological Systems into the Grand Scheme of Medicine, Biology, Pharmacology, and Toxicology, Exp. Biol. Med., 242:1559-1572, 2017. PMCID: PMC5661772 DOI

2016:

Brown JA, Codreanu GS, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP, Metabolic Consequences of Inflammatory Disruption of the Blood-Brain Barrier in an Organ-on-Chip Model of the Human Neurovascular Unit, J. Neuroinflammation, 13:306 , 2016. PMCID: PMC5153753 DOI

Choi H, Puvenna V, Brennan C, Mahmoud S, Wang X-F, Phillips M, Janigro D, Mazzone P, S100B and S100B Autoantibody as Biomarkers for Early Detection of Brain Metastases in Lung Cancer, Transl. Lung Cancer Res., 5:413-419, 2016. PMCID: PMC5009084 DOI

Dadas A, Washington J, Marchi N, Janigro D, Improving the Clinical Management of Traumatic Brain Injury Through the Pharmacokinetic Modeling of Peripheral Blood Biomarkers, Fluids Barriers CNS, 13:21, 2016. PMCID: PMC5402680 DOI

Ghosh C, Hossain M, Solanki J, Dadas A, Marchi N, Janigro D, Pathophysiological Implications of Neurovascular P450 in Brain Disorders, Drug Discov. Today, 21:1609-1619, 2016. PMCID: PMC5067181 DOI

Hines KM, May JC, McLean JA, Xu L, Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry, Anal. Chem. 88:7329-7336, 2016. PMCID: PMC4955523 DOI

Hutson MS, Alexander PG, Allwardt V, Aronoff DM, Bruner-Tran KL, Cliffel DE, Davidson JM, Gough A, Markov DA, McCawley LJ, McKenzie JR, McLean JA, Osteen KG, Pensabene V, Samson PC, Senutovitch NK, Sherrod SD, Shotwell MS, Taylor DL, Tetz LM, Tuan RS, Vernetti LA, Wikswo JP, Organs-on-Chips as Bridges for Predictive Toxicology, Appl. In Vitro Toxicol., 2:97-102, 2016. (Invited Review)  DOI

Lee JB, Balikov DA, Yang JW, Kim KS, Park HK, Kim JK, Kwon IK, Bellan LM, Sung HJ, Cationic Nanocylinders Promote Angiogenic Activities of Endothelial Cells, Polymers, 8:15, 2016. PMCID: PMC5639919 DOI

Lizama-Manibusan BN, Klein S, McKenzie JR, Cliffel DE, McLaughlin BA, Analysis of a Nitroreductase-Based Hypoxia Sensor in Primary Neuronal Cultures, ACS Chem. Neurosci., 7:1188-1191, 2016. PMCID: PMC5125302 DOI

Marchi N, Banjara M, Janigro D, Blood-Brain Barrier, Bulk Flow, and Interstitial Clearance in Epilepsy, J. Neurosci. Methods, 260:118-124, 2016. PMCID: PMC4835226 DOI

May JC, McLean JA, Advanced Multidimensional Separations in Mass Spectrometry: Navigating the Big Data Deluge, Annu. Rev. Anal. Chem., 9:387-409, 2016. PMCID: PMC5763907 DOI

Montenegro-Burke JR, Bennett JM, McLean JA, Hercules DM, Novel Behavior of the Chromatographic Separation of Linear and Cyclic Polymers, Anal. Bioanal. Chem., 408:677-681, 2016. PMCID: PMC4712628 DOI

Pensabene V, Costa L, Terekhov AY, Gnecco JS, Wikswo JP, Hofmeister WH, Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips, ACS Appl. Mater. Interfaces, 8:22629-22636, 2016. PMCID: PMC5131702 DOI

Puvenna V, Engeler M, Banjara M, Brennan C, Schreiber P, Dadas A, Bahrami A, Solanki J, Bandyopadhyay A, Morris JK, Bernick C, Ghosh C, Rapp E, Bazarian JJ, Janigro D, Is Phosphorylated Tau Unique to Chronic Traumatic Encephalopathy? Phosphorylated Tau in Epileptic Brain and Chronic Traumatic Encephalopathy, Brain Res., 1630:225-240, 2016. PMCID: PMC4853900 DOI

Schrimpe-Rutledge AC, Codreanu SG, Sherrod SD, McLean JA, Untargeted Metabolomics Strategies-Challenges and Emerging Directions, J Am Soc Mass Spectrom., 27:1897-1905, 2016. PMCID: PMC5110944 DOI

Sherrod SD, McLean JA, Systems-Wide High-Dimensional Data Acquisition and Informatics Using Structural Mass Spectrometry Strategies, Clin. Chem., 62:77-83, 2016. PMCID: PMC4843518 DOI

Sobolik T, Su Y, Ashby W, Schaffer DK, Wells S, Wikswo JP, Zijlstra A, Richmond A, Development of Novel Murine Mammary Imaging Windows to Examine Wound Healing Effects on Leukocyte Trafficking in Mammary Tumors with Intravital Imaging, IntraVital, 5:e1125562, 2016. PMCID: PMC5226013 DOI

2015:

Brown JA, Pensabene V, Markov DA, Allwardt V, Neely DM, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, Bowman AB, Reiserer RS, Wikswo JP, Recreating Blood-Brain Barrier Physiology and Structure On Chip: A Novel Neurovascular Microfluidic Bioreactor, Biomicrofluidics, 9:054124, 2015. PMCID: PMC4627929 DOI

Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee J-B, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung H-K, Hong CC, Combinatorial Polymer Matrices Enhance In Vitro Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Biomaterials, 67:52-64, 2015. PMCID: PMC4550551 DOI

Chun YW, Voyles DE, Rath R, Hofmeister LH, Boire TC, Wilcox H, Lee JH, Bellan LM, Hong CC, Sung HJ, Differential Responses of Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Anisotropic Strain Depends on Disease Status, J. Biomech., 48:3890-3896, 2015. PMCID: PMC4655132 DOI

Drake KJ, Shotwell MS, Wikswo JP, Sidorov VY, Glutamine and Glutamate Limit the Shortening of Action Potential Duration in Anoxia-Challenged Rabbit Hearts, Phys. Rep., 3(9):e12535, 2015 PMCID: PMC4600381 DOI

Falcone T, Carlton E, Lee C, Janigro M, Fazio V, Forcen FE, Franco K, Janigro D, Does Systemic Inflammation Play a Role in Pediatric Psychosis?, Clin. Schizophr. Relat. Psychoses, 9:65-78B, 2015 PMCID: PMC4899842

Falcone T, Janigro D, Lovell R, Simon B, Brown CA, Herrera M, Myint AM, Anand A, S100B Blood Levels and Childhood Trauma in Adolescent Inpatients, J. Psychiatr. Res., 62:14-22, 2015. PMCID: PMC4413930 DOI

French WR, Zimmerman LJ, Schilling B, Gibson BW, Miller CA, Townsend RR, Sherrod SD, Goodwin CR, McLean JA, Tabb DL, Wavelet-Based Peak Detection and a New Charge Inference Procedure for MS/MS Implemented in ProteoWizard’s msConvert, J. Proteome Res., 14:1299-1307, 2015. PMCID: PMC4324452 DOI

Ghosh C, Hossain M, Spriggs A, Ghosh A, Grant GA, Marchi N, Perucca E, Janigro D, Sertraline-Induced Potentiation of the CYP3A4-Dependent Neurotoxicity of Carbamazepine: An In Vitro Study, Epilepsia, 56:439-449, 2015. PMCID: PMC4413932 DOI

Gies AP, Stow SM, McLean JA, Hercules DM, MALDI-TOF/TOF CID Study of Poly(1,4-dihydroxybenzene terephthalate) Fragmentation Reactions, Polymer, 64:100-111, 2015. PMCID: PMC4505186 DOI

Goodwin CR, Covington BC, Derewacz DK, McNees CR, Wikswo JP, McLean JA, Bachmann BO, Structuring Microbial Metabolic Responses to Multiplexed Stimuli Via Self-Organizing Metabolomics Maps, Chem. Biol., 22:661-670 2015. PMCID: PMC4537791 DOI

Hofmeister LH, Lee SH, Norlander AE, Montaniel KR, Chen W, Harrison DG, Sung HJ, Phage-Display-Guided Nanocarrier Targeting to Atheroprone Vasculature, ACS Nano, 9:4435-4446, 2015. PMCID: PMC4654777 DOI

Hofmeister LH, Costa L, Balikov DA, Crowder SW, Terekhov A, Sung HJ, Hofmeister WH, Patterned Polymer Matrix Promotes Stemness and Cell-Cell Interaction of Adult Stem Cells, J. Biol. Eng. 9:18, 2015. PMCID: PMC4603908 DOI

Kumar KK, Goodwin CR, Uhouse MA, Bornhorst J, Schwerdtle T, Aschner M, McLean JA, Bowman AB, Untargeted Metabolic Profiling Identifies Interactions Between Huntington’s Disease and Neuronal Manganese Status, Metallomics, 7:363-370, 2015. PMCID: PMC4326616 DOI

Marasco CC, Enders JR, Seale KT, McLean JA, Wikswo JP, Real-Time Cellular Exometabolome Analysis with a Microfluidic-Mass Spectrometry Platform, PLoS ONE, 10(2):e0117685, 2015. https://doi.org/10.1371/journal.pone.0117685 PMCID: PMC4344306 DOI

May JC, Goodwin CR, McLean JA, Ion Mobility-Mass Spectrometry Strategies for Untargeted Systems, Synthetic, and Chemical Biology, Curr. Opin. Biotechnol., 31:117-121, 2015, PMCID: PMC4297680 DOI

May JC, Dodds JN, Kurulugama RT, Stafford GC, Fieldsted JC, McLean JA, Broadscale Resolving Power Performance of a High Precision Uniform Field Ion Mobility-Mass Spectrometer, Analyst, 140:6824-6833, 2015.  PMCID: PMC4586486 DOI

May JC, McLean JA, Ion Mobility-Mass Spectrometry: Time-Dispersive Instrumentation, Anal. Chem., 87:1422-1436, 2015. PMCID: PMC4318620 DOI

May JC, McLean JA, A Uniform Field Ion Mobility Study of Melittin and Implications of Low-Field Mobility for Resolving Fine Cross-Sectional Detail in Peptide and Protein Experiments, Proteomics, 15:2862-2871, 2015  DOI

McKenzie JR, Cognata AC, Davis AN, Wikswo JP, Cliffel DE, Real-Time Monitoring of Cellular Bioenergetics with a Multianalyte Screen-Printed Electrode, Anal. Chem., 87:7857-7864, 2015. PMCID: PMC4770793 I DOI

Patel D, Naik R, Boyer R, Wikswo J, Vasilevskis E, Methods To Identify Saline-Contaminated Electrolyte Profiles, Clin. Chem. Lab. Med., 53:1585-1591, 2015. PMCID: PMC4544643 DOI

Stow SM, Onifer TM, Forsythe JG, Nefzger H, Kwiecien NW, May JC, McLean JA, Hercules DM, Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies: 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers, Anal. Chem., 87:6288-6296, 2015 PMCID: PMC5642105 DOI

Wikswo JP, Porter AP, Biology Coming Full Circle: Joining the Whole and the Parts, Exp. Biol. Med, 240:3-7, 2015. PMC4391629 DOI

Wilkerson I et al., Retinal Pericytes and Cytomegalovirus Infectivity: Implications for HCMV-Induced Retinopathy and Congenital Ocular Disease, J. Neuroinflammation, 12:2, 2015, PMCID: PMC4314746

Xu L, Kliman M, Forsythe JG, Korade Z, Hmelo AB, Porter NA, McLean JA, Profiling and Imaging Ion Mobility-Mass Spectrometry Analysis of Cholesterol and 7-Dehydrocholesterol in Cells Via Sputtered Silver MALDI, J. Amer. Soc. Mass Spec., 26:924-933, 2015. PMCID: PMC4608680 DOI

2014:

Hendricks NG, Lareau NM, Stow SM, McLean JA, Julian RR, Bond-Specific Dissociation Following Excitation Energy Transfer for Distance Constraint Determination in the Gas Phase, J. Am. Chem. Soc., 136:13363-13370, 2014. PMCID: PMC4183596 DOI

Lee SH, Lee Y, Chun YW, Crowder SW, Young PP, Park KD, Sung HJ, In Situ Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells, Adv. Funct. Mater., 24:6771-6781, 2014. PMCID: PMC4551405 DOI

Boussadia B et al., Effect of Status epilepticus and Antiepileptic Drugs on CYP2E1 Brain Expression, Neuroscience, 281C:124-134, 2014

Brown JA et al., Metabolic Consequences of Interleukin-6 Challenge in Developing Neurons and Astroglia, J. Neuroinflammation, 11:183, 2014, PMCID: PMC4233071

Byrd TF et al., The Microfluidic Multitrap Nanophysiometer for Hematologic Cancer Cell Characterization Reveals Temporal Sensitivity of the Calcein-AM Efflux Assay, Sci. Rep., 4:Article 5117, 2014, PMCID: PMC4038811

Crowder SW, Balikov DA, Hwang Y, Sung HJ, Cancer Stem Cells Under Hypoxia as a Chemoresistant Factor in Breast and Brain, Curr. Pathobiol. Rep., 2:33-40, 2014, PMCID: PMC3935368

Evans C et al., Phosphorylation of Serine 106 in Asef2 Regulates Cell Migration and Adhesion Turnover, J. Proteome Res., 13:3303-3313, 2014, PMCID: PMC4084842

Forsythe JG et al., Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies: I. Electrospray Spectra of 2-Ring Isomers, Anal. Chem., 86:4362-4370, 2014, PMCID: PMC4014176

Goodwin CR et al., Phenotypic Mapping of Metabolic Profiles Using Self-Organizing Maps of High-Dimensional Mass Spectrometry Data, Anal. Chem., 86:6561-6571, 2014, PMCID: PMC4082383

Hines KM, Ballard BR, Marshall DR, McLean JA, Structural Mass Spectrometry of Tissue Extracts to Distinguish Cancerous and Non-Cancerous Breast Diseases, Mol. BioSyst., 10:2827-2837, 2014, PMCID: PMC3267852

Hockemeyer K et al., Engineered Three-Dimensional Microfluidic Device for Interrogating Cell-Cell Interactions in the Tumor Microenvironment, Biomicrofluidics, 8:044105-1, 2014, PMCID: PMC4189212

Irvin MW, Zijlstra A, Wikswo JP, Pozzi A, Techniques and Assays for the Study of Angiogenesis, Exp. Biol. Med., 239:1476-1488, 2014 (Invited Review), PMCID: PMC4216737

Lima EA et al., Multichamber Multipotentiostat System for Cellular Microphysiometry, Sensor. Actuat. B-Chem., 204:536-543, 2014, PMCID: PMC4167374

Ly DL, Lipson H, Optimal Experiment Design for Coevolutionary Active Learning, IEEE Trans. Evol. Comput., 18:394- 404, 2014

Marasco CC et al., Systems-Level View of Cocaine Addiction: The Interconnection of the Immune and Nervous Systems, Exp. Biol. Med., 239:1433-1442, 2014 (Invited Review), PMCID: PMC4216763

Markov DA, Lillie EM, Garbett SP, McCawley LJ, Variation in Diffusion of Gases Through PDMS Due to Plasma Surface Treatment and Storage Conditions, Biomed. Microdevices, 16:91-96, 2014, PMCID: PMC3945670

May JC et al., Conformational Ordering of Biomolecules in the Gas-Phase: Nitrogen Collision Cross-Sections Measured on a Prototype High Resolution Drift Tube Ion Mobility-Mass Spectrometer, Anal. Chem., 86:2107-2116, 2014, PMCID: PMC3931330

Puvenna V et al., Significance of Ubiquitin Carboxy-Terminal Hydrolase L1 Elevations in Athletes after Sub-Concussive Head Hits, PLoS ONE, 9e96296, 2014, PMCID: PMC4012998

Wang X et al., Polymeric Stent Materials Dysregulate Macrophage and Endothelial Cell Functions: Implications for Coronary Artery Stent, Int. J. Cardiol., 4:688-695, 2014, PMCID: PMC4070878

Wikswo JP, The Relevance and Potential Roles of Microphysiological Systems in Biology and Medicine, Exp. Biol. Med., Annual Thematic Issue: The Biology and Medicine of Microphysiological Systems, 239:1061-1072, 2014   DOI

Yan Y et al., A Microfluidic-Enabled Mechanical Microcompressor for the Immobilization of Live Single- and Multi-Cellular Specimens, Microsc. Microanal., 20:141-151, 2014, PMCID: PMC4026272

Zachman AL et al., Femtosecond Laser-Patterned Nanopore Arrays for Surface-Mediated Peptide Treatment, Nanomedicine: NBM, 10:11-14, 2014, PMCID: PMC3877160

Zachman AL et al., Uncoupling Angiogenesis and Inflammation in Peripheral Artery Disease with Therapeutic Peptide-Loaded Microgels, Biomaterials, 35:9635-9648, 2014, PMCID: PMC4164579

2013:

Shinawi TF, Kimmel DW, Cliffel DE, Multianalyte Microphysiometry Reveals Changes in Cellular Bioenergetics upon Exposure to Fluorescent Dyes, Anal. Chem. 85:11677-11680, 2013.  PMCID: PMC3900241 DOI

Alcendor et al., Neurovascular Unit on a Chip: Implications for Translational Applications, Stem Cell Res. & Ther., 4(Suppl 1):S18, 2013, PMCID: PMC4029462 

Chattopadhyay I and Lipson H, Abductive Learning of Quantized Stochastic Processes With Probabilistic Finite Automata, Phil. Trans. R. Soc. A, 371: 20110543, 2013   DOI

Chattopadhyay I, Kuchina A, Suel G, Lipson H, Inverse Gillespie for Inferring Stochastic Reaction Mechanisms from Intermittent Samples, PNAS 110:12990-12995, 2013, PMCID: PMC3740874 

Chowdhury S, Svec P, Wang C, Seale KT, Wikswo JP, Losert W, Gupta SK, Automated Cell Transport in Optical Tweezers-Assisted Microfluidic Chambers, IEEE T-ASE, 10:980-989, 2013 

Cornforth TW, Lipson H, Inference of Hidden Variables in Systems of Differential Equations with Genetic Programming, Genet. Program. Evolvable Mach., 14:155-190, 2013  

Crowder SW et  al., Three-Dimensional Graphene Foams Promote Osteogenic Differentiation of Human Mesenchymal Stem Cells, Nanoscale, 5:4171-4176, 2013, PMCID: PMC3672224 

Crowder SW et  al., Poly(ϵ-caprolactone)-Carbon Nanotube Composite Scaffolds for Enhanced Cardiac Differentiation of Human Mesenchymal Stem Cells, Nanomed., 8:1763-1776, 2013, PMCID: PMC3809159 

Cucullo L, Hossain M, Tierney W, Janigro D, A New Dynamic In Vitro Modular Capillaries-Venules Modular System: Cerebrovascular Physiology in a Box, BMC Neurosci., 14:18, 2013, PMCID: PMC3598202 

Deng J, Dhummakupt A, Samson P, Wikswo JP, Shor LM, Dynamic Dosing Assay Relating Real-Time Respiration Responses of Staphylococcus aureus Biofilms to Changing Microbial Conditions, Anal. Chem., 85:5411-5419, 2013

Derewacz DK et al., Antimicrobial Drug Resistance Affects Broad Changes in Metabolomic Phenotype in Addition to Secondary Metabolism, PNAS, 110, 2336-2341, 2013, PMCID: PMC3568320   DOI

Wikswo JP et al., Scaling and Systems Biology for Integrating Multiple Organs-on-a-Chip, Lab Chip,13:3496-3511, 2013, PMCID: PMC3818688   DOI    PDF

Wikswo JP et al. Engineering Challenges for Instrumenting and Controlling Integrated Organ-on-a-Chip Systems, IEEE Trans. Biomed. Eng., 60, 682-690, 2013, PMCID: PMC3696887  DOI              Full Text

Woods MC, Uzelac I, Holcomb MR, Wikswo JP, Sidorov VY, Diastolic Field Stimulation: The Role of Shock Duration in Epicardial Activation and Propagation, Biophys. J., 105:523-532, 2013, PMCID: PMC3714876

Zachman AL, Page JM, Prabhakar G, Guelcher SA, Sung HJ, Elucidation of Adhesion-Dependent Spontaneous Apoptosis in Macrophages Using Phase Separated PEG/Polyurethane Films, Acta Biomater., 9:4964-4975, 2013, PMCID: PMC3606556

2012 :

Ashby WJ, Zijlstra A, Established and Novel Methods of Interrogating Two-Dimensional Cell Migration, Integr. Biol., 4:1338-1350, 2012, PMCID: PMC3444626  DOI

Ashby W, Wikswo JP, Zijlstra A, Magnetically Attachable Stencils and the Non-Destructive Analytis of the Contribution Made by the Underlying Matrix to Cell Migration, Biomaterials, 33:8189-8203, 2012  DOI

Chumbler NM et al., Clostridium Difficile Toxin B Causes Epithelial Cell Necrosis Through an Autoprocessing-Independent Mechanism, PLoS Pathog., 8:Article e1003072, 2012, PMCID: PMC3516567   DOI

Drake KJ et al., Amino Acids As Metabolic Substrates During Cardiac Ischemia, Exp. Biol. Med., 237:1369-1378, 2012, PMCID: PMC3816490   DOI

Enders JR et al., A Dual-Column Solid Phase Extraction Strategy for Online Collection and Preparation of Continuously Flowing Effluent Streams for Mass Spectrometry, Anal. Chem., 84:8467-8474, 2012, PMCID: PMC3518407   DOI

Forsythe JG et al., Semitransparent Nanostructured Films for Imaging Mass Spectrometry and Optical Microscopy, Anal. Chem., 84:10665-10670, 2012, PMCID: PMC3544556   DOI

Ges IA, Currie KP, Baudenbacher F, Electrochemical Detection of Catecholamine Release Using Planar Iridium Oxide Electrodes in Nanoliter Microfluidic Cell Culture Volumes, Biosens. Bioelectron., 34:30-36, 2012, PMCID: PMC3793634    DOI

Goodwin CR et al., Structural Mass Spectrometry: Rapid Methods for Separation and Analysis of Peptide Natural Products, J. Nat. Prod., 75:48-53, 2012, PMCID: PMC3267852   DOI

Harkness KM et al., Biomimetic Monolayer-Protected Gold Nanoparticles for Immunorecognition, Nanoscale, 4:3843-3851, 2012, PMCID: PMC3376232  DOI

Harkness KM et al., Ag-44(SR)304-: A Silver-Thiolate Superatom Complex, Nanoscale, 4:4269-4274, 2012, PMCID: PMC3518420  DOI

Harry RS et al., Metabolic Impact of 4-Hydroxynonenal on Macrophage-Like RAW 264.7 Function and Activation, Chem. Res. Toxicol., 25:1643-1651, 2012, PMCID: PMC3444243  DOI

Hiatt LA et al., A Printed Superoxide Dismutase Coated Electrode for the Study of Macrophage Oxidative Burst, Biosens. Bioelectron., 33:128-133, 2012, PMCID: PMC3291099  DOI

Holcomb MR et al., Continuous-Waveform Constant-Current Isolated Physiological Stimulator, Rev. Sci. Instrum., 83:044303, 2012, PMCID: PMC3331867  DOI

Janigro D, Are You In or Out? Leukocyte, Ion, and Neurotransmitter Permeability Across the Epileptic Blood-Brain Barrier, Epilepsia, 53 Suppl 1:26-34, 2012, PMCID: PMC4093790  DOI

Kimmel DW, LeBlanc G, Meschievitz ME, Cliffel DE, Electrochemical Sensors and Biosensors, Anal. Chem., 84:685-707, 2012 (Invited Review)   DOI

Ly DL, Lipson H, Learning Symbolic Representations of Hybrid Dynamical Systems, J. Mach. Learn. Res., 13, 3585-3618, 2012   PDF

Markov DA, Lu JP, Samson PC, Wikswo JP, McCawley LJ, Thick-Tissue Bioreactor As a Platform for Long-Term Organotypic Culture and Drug Delivery, Lab Chip, 12:4560-4568, 2012, PMCID: PMC3826880  DOI

Mashburn DN, Lynch HE, Ma X, Hutson MS, Enabling User-Guided Segmentation and Tracking of Surface-Labeled Cells in Time-Lapse Image Sets of Living Tissues, Cytometry A, 81A:409-418, 2012, PMCID: PMC3331924   DOI

Matusch A et al., Combined Elemental and Biomolecular Mass Spectrometry Imaging (MSI)  for Probing the Inventory of Tissue at the Micrometer Scale, Anal. Chem., 84:3170-3177, 2012  DOI

McKenzie JR, Palubinsky AM, Brown JE, McLaughlin BM, Cliffel DE, Metabolic Multianalyte Microphysiometry Reveals Extracellular Acidosis Is an Essential Mediator of Neuronal Preconditioning, ACS Chem. Neurosci., 3:510-518, 2012, PMCID: PMC3399578  DOI

Venkataraman R, Holcomb MR, Harder R, Knollmann BC, Baudenbacher F, Ratiometric Imaging of Calcium During Ischemia-Reperfusion Injury in Isolated Mouse Hearts Using Fura-2, Biomed. Eng. Online, 11:Article 39, 2012, PMCID: PMC3466138   

2011:

Fenn,LS and McLean,JA. Structural Resolution of Carbohydrate Positional and Structural Isomers Based on Gas-Phase Ion Mobility-Mass Spectrometry, Phys. Chem. Chem. Phys., 13, 2196-2205, 2011   DOI

Velkovsky,M, Snider,R, Cliffel,DE, Wikswo,JP. Modeling the Measurements of Cellular Fluxes in Microbioreactor Devices Using Thin Enzyme Electrodes, Journal of Mathematical Chemistry, 49, 251-275, 2011, PMCID: PMC3768171   DOI

Gupta, MK et al., Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation, PLoS ONE, 6(12): e28935, 2011 

LeDuc,PR, Messner,WC, Wikswo,JP. How Do Control-Based Approaches Enter into Biology?, Annu. Rev. Biomed. Engr., 13, 369-396, 2011  DOI

Yang,R, Lenaghan,SC, Wikswo,JP, Zhang,M. External Control of the GAL Network in S. Cerevisiae:  A View From Control Theory, PloS. One., 6, e19353, 2011, PMCID: PMC3084829  DOI

Dukes III,AD, Samson,PC, Keene,JD, Davis,LM, Wikswo,JP, Rosenthal,SJ. Single-Nanocrystal Spectroscopy of White-Light-Emitting CdSe Nanocrystals, The Journal of Physical Chemistry A, 115, 4076-4081, 2011  DOI

Gao,Y, Majumdar,D, Jovanovic,B, Shaifer,C, Lin,P, Zijlstra,A, Webb,D, Li,D. A Versatile Valve-Enabled Microfluidic Cell Co-Culture Platform and Demonstration of Its Applications to Neurobiology and Cancer Biology, Biomed. Microdevices, 13, 539-548, 2011  DOI

Sidorov,VY, Uzelac,I, Wikswo,JP. Regional Increase of Extracellular Potassium Leads to Electrical Instability and Reentry Occurrence Through the Spatial Heterogeneity of APD Restitution, Am. J. Physiol. Heart, 301, H209-H220, 2011, PMCID: PMC3129923  DOI

Liu,Y, Markov,D, Wikswo,J, McCawley,L. Microfabricated Scaffold-Guided Endothelial Morphogenesis in Three-Dimensional Culture, Biomed. Microdevices, 13, 837-846, 2011  DOI

Schmidt,MD, Vallabhajosyula,RR, Jenkins,JW, Hood,JE, Soni,AS, Wikswo,JP, Lipson,H. Auotmated Refinement and Inference of Analytical Models for Metabolic Networks, Phys. Biol., 8, 055011 2011, PMCID: PMC4109817  DOI

Kerr,TJ, Gant-Branum,RL, McLean,JA. Multiplexed Analysis of Peptide Functionality Using Lanthanide-Based Structural Shift Reagents, Int. J. Mass Spectrom., 307, 28-32, 2011, PMCID: PMC3182153  DOI

Kliman,M, May,JC, McLean,JA. Lipid Analysis and Lipidomics by Structurally Selective Ion Mobility-Mass Spectrometry, Biochimica Et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1811, 935-945, 2011, PMCID: PMC3326421  DOI

Lubbers,B and Baudenbacher,F. Isothermal Titration Calorimetry in Nanoliter Droplets With Subsecond Time Constants, Anal. Chem., 80, 7955-7961, 2011, PMCID: PMC3737424  DOI

Harkness,KM et al. Nanoscale Phase Segregation of Mixed Thiolates on Gold Nanoparticles, Angew. Chem. -Int. Ed., 50, 10554-10559, 2011, PMCID: PMC3518417  DOI

Azevedo,D et al. DRhoGEF2 Regulates Cellular Tension and Cell Pulsations in the Amnioserosa During Drosophila Dorsal Closure, PloS. One., 6, Article e23964, 2011  DOI

Jayasinghe,AK, Rohner,J, Hutson,MS. Holographic UV Laser Microsurgery, Biomed. Opt. Express, 2, 2590-2599, 2011  DOI  

2010:

Addae-Mensah,KA, Retterer,S, Opalenik,S, Thomas,D, Lavrik,NV, Wikswo,JP. Cryogenic Etching of Silicon:  an Alternative Method for Fabrication of Vertical Microcantilever Master Molds, J. Microelectromech. S., 19, 64-74, 2010, PMCID: PMC3818692   DOI

Ayati,BP, Edwards,CM, Webb,GF, Wikswo,JP. A Mathematical Model of Bone Remodeling Dynamics for Normal Bone Cell Populations and Myeloma Bone Disease, Biology Direct, 5, 28 2010, PMCID: PMC2867965   DOI

Darby,S, Moore,M, Wikswo,JP, Reiserer,R, Friedlander,T, Schaffer,DK, Seale,KT. A Metering Rotary Nanopump for Microfluidic Systems, Lab Chip, 10, 3218-3226, 2010, PMCID: PMC4156019  DOI

Enders,JR, Marasco,CC, Kole,A, Nguyen,B, Sundarapandian,S, Seale,KT, Wikswo,JP, McLean,JA. Towards Monitoring Real-Time Cellular Response Using an Integrated Microfluidics-MALDI/NESI-Ion Mobility-Mass Spectrometry Platform, IET Syst. Biol., 4, 416-427, 2010, PMCID: PMC4254925   DOI

Gant-Branum,RL, Broussard,JA, Mahsut,A, Webb,DJ, McLean,JA. Identification of Phosphorylation Sites Within the Signaling Adaptor APPL1 by Mass Spectrometry, J. Proteome. Res., 9, 1541-1548, 2010, PMCID: PMC2845304   DOI

Ges,IA and Baudenbacher,F. Enzyme Electrodes to Monitor Glucose Consumption of Single Cardiac Myocytes in Sub-Nanoliter Volumes, Biosens. Bioelectron., 25, 1019-1024, 2010, PMCID: PMC4119477   DOI

Ges,IA and Baudenbacher,F. Enzyme-Coated Microelectrodes to Monitor Lactate Production in a Nanoliter Microfluidic Cell Culture Device, Biosens. Bioelectron., 26, 828-833, 2010  DOI   

Harkness,KM, Fenn,LS, Cliffel,DE, McLean,JA. Surface Fragmentation of Complexes From Thiolate Protected Gold Nanoparticles by Ion Mobility-Mass Spectrometry, Anal. Chem., 82, 3061-3066, 2010, PMCID: PMC2848286   DOI

Harkness,KM, Hixson,BC, Fenn,LS, Turner,BN, Rape,AC, Simpson,CA, Huffman,BJ, Okoli,TC, McLean,JA, Cliffel,DE. A Structural Mass Spectrometry Strategy for the Relative Quantitation of Ligands on Mixed Monolayer-Protected Gold Nanoparticles, Anal. Chem., 82, 9268-9274, 2010, PMCID: PMC2980554   DOI

Harkness,KM, Cliffel,DE, McLean,JA. Characterization of Thiolate-Protected Gold Nanoparticles by Mass Spectrometry, The Analyst, 135, 868-874, 2010, PMCID: PMC4041160   DOI

Jowhar,D, Wright,G, Samson,PC, Wikswo,JP, Janetopoulos,C. Open Access Microfluidic Device for the Study of Cell Migration During Chemotaxis, Integrative Biology, 2, 648-658, 2010, PMCID: PMC3806978   DOI

Kerr,TJ and McLean,JA. Peptide Quantitation Using Primary Amine Selective Metal Chelation Labels for Mass Spectrometry, Chem. Commun., 46, 5479-5481, 2010   DOI

Kliman,M, Vijayakrishnan,N, Wang,L, Tapp,JT, Broadie,K, McLean,JA. Structural Mass Spectrometry Analysis of Lipid Changes in a Drosophila Epilepsy Model Brain, Mol. Biosyst., 6, 958-966, 2010, PMCID: PMC3848785   DOI

Markov,DA, Samson,PC, Schaffer,DK, Dhummakup,A, Wikswo,JP, Shor,LM. Window on a Microworld: Simple Microfluidic Systems for Studying Microbial Transport in Porous Media, JoVE, 39, 2010  DOI

Markov,DA, Manuel,S, Shor,L, Opalenik,SR, Wikswo,JP, Samson,PC. Tape Underlayment Rotary-Node (TURN) Valves for Simple on-Chip Microfluidic Flow Control, Biomed. Microdevices, 12, 135-144, 2010, PMCID: PMC3742084   DOI

McBride,KK, Roth,BJ, Sidorov,VY, Wikswo,JP, Baudenbacher,FJ. Measurements of Transmembrane Potential and Magnetic Field at the Apex of the Heart, Biophys. J., 99, 3113-3118, 2010, PMCID: PMC2980705   DOI

McLean,JR, Mclean,JA, Wu,ZX, Becker,C, Perez,LM, Pace,CN, Scholtz,JM, Russell,DH. Factors That Influence Helical Preferences for Singly Charged Gas-Phase Peptide Ions: The Effects of Multiple Potential Charge-Carrying Sites, J. Phys. Chem. B, 114, 809-816, 2010, PMCID: PMC2818683   DOI

Rachakonda,G, Sekhar,K, Jowhar,D, Samson,PC, Wikswo,JP, Beauchamp,RD, Sasi,S, Datta,PK, Freeman,ML. Increased Cell Migration and Plasticity in Nrf2 Deficient Cancer Cell Lines, Oncogene, 29, 3703-3714, 2010, PMCID: PMC2892014  DOI

Ridenour,WB, Kliman,M, McLean,JA, Caprioli,RM. Structural Characterization of Phospholipids and Peptides Directly From Tissue Sections by MALDI Traveling-Wave Ion Mobility-Mass Spectrometry, Anal. Chem., 82, 1881-1889, 2010, PMCID: PMC2830338   DOI  

Seale,KT, Faley,SL, Chamberlain,J, Wikswo,JP, Jr. Macro to Nano:  A Simple Method for Transporting Cultured Cells From Milliliter Scale to Nanoliter Scale, Exp. Biol. Med., 235, 777-783, 2010, PMCID: PMC4109816  DOI  

Snider,RM, McKenzie,JR, Kraft,L, Kozlov,E, Wikswo,JP, Cliffel,DE. The Effects of Cholera Toxin on Cellular Energy Metabolism, Toxins, 2, 632-648, 2010, PMCID: PMC3153216   DOI

Sundarapandian,S, May,JC, McLean,JA. Dual Source Ion Mobility-Mass Spectrometer for Direct Comparison of Electrospray Ionization and MALDI Collision Cross Section Measurements, Anal. Chem., 82, 3247-3254, 2010, PMCID: PMC2855557   DOI

Brodland,GW et al. Video Force Microscopy Reveals the Mechanics of Ventral Furrow Invagination in Drosophila, PNAS (US), 107, 22111-22116, 2010  DOI  

2009:

Fenn,LS, Kliman,M, Mahsut,A, Zhao,SR, McLean,JA. Characterizing Ion Mobility-Mass Spectrometry Conformation Space for the Analysis of Complex Biological Samples, Analytical and Bioanalytical Chemistry, 394, 235-244, 2009, PMCID: PMC2762638   DOI

Irimia,A, Swinney,KR, Wikswo,JP. Partial Independence of Bioelectric and Biomagnetic Fields and Its Implications for Encephalography and Cardiography, Phys. Rev. E, 79, 051908, 2009, PMCID: PMC3818693  DOI

Eklund,SE, Thompson,RG, Snider,RM, Carney,CK, Wright,DW, Wikswo,J, Cliffel,DE. Metabolic Discrimination of Select List Agents by Monitoring Cellular Responses in a Multianalyte Microphysiometer, Sensors, 9, 2117-2133, 2009, PMCID: PMC3345856   DOI

Ma,X, Lynch,H, Scully,PC, Hutson,MS. Probing Embryonic Tissue Mechanics With Laser Hole Drilling. Physical Biology, 6, 036004, 2009  DOI

An,SS, Kim,J, Ahn,K, Trepat,X, Drake,KJ, Kumar,S, Ling,G, Purington,C, Rangasamy,T, Kensler,TW et al. Cell Stiffness, Contractile Stress and the Role of the Extracellular Matrix, Biochem. Biophys. Res. Commun., 382, 697-703, 2009, PMCID: PMC2956180  DOI

Botzolakis,EJ, Maheshwari,A, Feng,HJ, Lagrange,AH, Shaver,JH, Kassebaum,NJ, Venkataraman,R, Baudenbacher,F, MacDonald,RL. Achieving Synaptically Relevant Pulses of Neurotransmitter Using PDMS Microfluidics, J. Neurosci. Methods, 177, 294-302, 2009   DOI

Elzie,CA, Colby,J, Sammons,MA, Janetopoulos,C. Dynamic Localization of G Proteins in Dictyostelium Discoideum, J. Cell Sci., 122, 2597-2603, 2009  DOI

Faley,SL, Copland,M, Wlodkowic,D, Kolch,W, Seale,KT, Wikswo,JP, Cooper,JM. Microfluidic Single Cell Arrays to Interrogate Signalling Dynamics of Individual, Patient-Derived Hematopoietic Stem Cells, Lab Chip, 9, 2659-2664, 2009  DOI

Gray,RA, Wikswo,JP, Otani,NF. Origin Choice and Petal Loss in the Flower Garden of Spiral Wave Tip Trajectories, Chaos, 19, 033118 2009, PMCID: PMC2748696   DOI

McLean,JA. The Mass-Mobility Correlation Redux:  the Conformational Landscape of Anhydrous Biomolecules, J. Am. Soc. Mass. Spect., 20, 1775-1781, 2009  DOI

Gant-Branum,RL, Kerr,TJ, McLean,JA. Labeling Strategies in Mass Spectrometry-Based Protein Quantitation, Analyst, 134, 1525-1530 (2009) 10.1039/B904643G   DOI

Easley,CJ, Benninger,RKP, Shaver,JH, Steven Head,W, Piston,DW. Rapid and Inexpensive Fabrication of Polymeric Microfluidic Devices Via Toner Transfer Masking, Lab Chip, 9, 1119-1127, 2009   DOI

Enders,JR and McLean,JA. Chiral and Structural Analysis of Biomolecules Using Mass Spectrometry and Ion Mobility-Mass Spectrometry, Chirality, 21, E253-E264, 2009   DOI

Fenn,LS and McLean,JA. Simultaneous Glycoproteomics on the Basis of Structure Using Ion Mobility-Mass Spectrometry, Mol. Biosyst., I5, 1298-1302, 2009   DOI

Holcomb,MR, Woods,MC, Uzelac,I, Wikswo,JP, Gilligan,JM, Sidorov,VY. The Potential of  Dual Camera System for Multimodal Imaging of Cardiac Electrophysiology and Metabolism, Exp. Biol. Med., 234, 1355-1373, 2009, PMCID: PMC3816393   DOI

Wlodkowic,D, Faley,S, Zagnoni,M, Wikswo,JP, Cooper,JM. Microfluidic Single-Cell Array Cytometry for the Analysis of Tumour Apoptosis, Anal. Chem., 81, 5517-5523, 2009, PMCID: PMC3816605   DOI

Hutson,MS, Veldhuis,J, Ma,X, Lynch,HE, Cranston,PG, Brodland,GW. Combining Laser Microsurgery and Finite Element Modeling to Assess Cell-Level Epithelial Mechanics, Biophys. J., 97, 3075-3085, 2009  DOI

2008:

Wang,W, Shor,LM, LeBoeuf,EJ, Wikswo,JP, Taghon,GL, Kosson,DS. Protozoan Migration in Bent Microfluidic Channels, Appl. Environ. Microbiol., 74, 1945-1949, 2008, PMCID: PMC2268297   DOI

Gorman,BR and Wikswo,JP, Characterization of Transport in Microfluidic Gradient Generator, Microfluidics and Nanofluidics,  4, 273-285, 2008   DOI

Abbas,RA, Lin,S-F, Mashburn,D, Xu,J, Wikswo,JP, A Phased-Array Stimulator System for Studying Planar and Curved Cardiac Activation Wave Fronts, IEEE Trans. Biomed. Eng., 55: 222-229, 2008, PMCID: PMC2742885  DOI

Addae-Mensah,KA and Wikswo,JP. Measurement Techniques for Cellular Biomechanics In Vitro, Experimental Biology and Medicine, 233, 792-809, 2008  DOI

Georgescu W, Jourquin J, Estrada L, Anderson ARA, Quaranta V, Wikswo JP, Model-Controlled Hydrodynamic Focusing to Generate Multiple Overlapping Gradients of Surface-Immobilized Proteins in Microfluidic Devices, Lab on a Chip, 8: 238-244,  2008  DOI

Evertson,DW, Holcomb,MR, Eames,M, Bray,M, Sidorov,VY, Xu,J, Wingard,H, Dobrovolny,HM, Woods,MC, Gauthier,DJ et al. High-Resolution High-Speed Panoramic Cardiac Imaging System, IEEE Trans. Biomed. Eng., 55, 1241-1243, 2008, PMCID: PMC2561274   DOI

Snider,RM, Ciobanu,M, Rue,AE, Cliffel,DE, A Multiwalled Carbon Nanotube/Dihydropyran Composite Film Electrode for Insulin Detection in a Microphysiometer Chamber, Anal.Chim.Acta, 609: 44-52, 2008, PMCID: PMC2358927  DOI

Ges,IA, Dzhura,IA, Baudenbacher,FJ. On-Chip Acidification Rate Measurements From Single Cardiac Cells Confined in Sub-Nanoliter Volumes, Biomed. Microdevices, 10, 347-354, 2008, PMCID: PMC4243529  DOI

Xu,J, Reiserer,R, Tellinghuisen,J, Wikswo,JP, Baudenbacher,FJ. A Microfabricated Nanocalorimeter:  Design, Characterization, and Chemical Calibration, Anal. Chem., 80, 2728-2733, 2008, PMCID: PMC4155943   DOI

Jayagopal,A, Sussman,EM, Shastri,VP. Functionalized Solid Lipid Nanoparticles for Trans-Endothelial Delivery, IEEE Trans. NanoBiosci., 7, 28-34, 2008   DOI

Diniz Oliveira,HF, Weiner,AA, Majumdar,A, Shastri,VP. Non-Covalent Surface Engineering of an Alloplastic Polymeric Bone Graft Material for Controlled Protein Release, Journal of Controlled Release, 126, 237-245, 2008   DOI

Gruver,JS, Wikswo,JP, Chung,CY. 3'-Phosphoinositides Regulate the Coordination of Speed and Accuracy During Chemotaxis, Biophys. J., 95, 4057-4067, 2008, PMCID: PMC2553113   DOI

Liu,Y, Sai,JG, Richmond,A, Wikswo,JP. Microfluidic Switching System for Analyzing Chemotaxis Responses of Wortmannin-Inhibited HL-60 Cells, Biomed. Microdevices, 10, 499-507, 2008, PMCID: PMC2668251  DOI

Harris,MP, Kim,E, Weidow,B, Wikswo,JP, Quaranta,V. Migration of Isogenic Cell Lines Quantified by Dynamic Multivariate Analysis of Single-Cell Motility, Cell Adhesion & Migration, 2, 127-136, 2008, PMCID: PMC2634586   DOI

Fenn,LS and McLean,JA. Biomolecular Structural Separations by Ion Mobility-Mass Spectrometry, Anal. Bioanal. Chem., 391, 905-909 (2008)   DOI

Fenn,LS and McLean,JA. Enhanced Carbohydrate Structural Selectivity in Ion Mobility-Mass Spectrometry Analyses by Boronic Acid Derivatization, Chem. Commun., Issue 43, 5505-5507 (2008)  DOI

Sai,J, Raman,D, Liu,Y, Wikswo,J, Richmond,A. Parallel Phosphatidylinositol 3-Kinase (PI3K)-Dependent and Src-Dependent Pathways Lead to CXCL8-Mediated Rac2 Activation and Chemotaxis, J. Biol. Chem., 283, 26538-26547, 2008, PMCID: PMC2546539  DOI

Ges,IA and Baudenbacher,F. Microfluidic Device to Confine Single Cardiac Myocytes in Sub-Nanoliter Volumes for Extracellular PH Measurements, J. Exp. Nanosci., 3, 63-75, 2008 DOI

Ciobanu,M, Taylor,DE, Wilburn,JP, Cliffel,DE. Glucose and Lactate Biosensors for Scanning Electrochemical Microscopy Imaging of Single Live Cells, Anal. Chem., 80, 2717-2727, 2008, PMCID: PMC2836715   DOI

Irimia,A and Wikswo,JP, Jr. Gastrointestinal Arrhythmias Are Associated With Statistically Significant Fluctuations in Systemic Information Dimension, Physiol. Meas., 29, N33-N40, 2008   DOI

Faley,S, Seale,K, Hughey,J, Schaffer,DK, VanCompernolle,S, McKinney,B, Baudenbacher,F, Unutmaz,D, Wikswo,JP. Microfluidic Platform for Real-Time Signaling Analysis of Multiple Single T Cells in Parallel, Lab Chip, 8, 1700-1712, 2008, PMCID: PMC4160168   DOI

Sidorov,VY, Holcomb,MR, Woods,MC, Gray,RA, Wikswo,JP. Effects of Unipolar Stimulation on Voltage and Calcium Distributions in the Isolated Rabbit Heart, Basic Research in Cardiology, 103, 537-551, 2008, PMCID: PMC2742888  DOI

Seale,KT, Reiserer,RS, Markov,DA, Ges,IA, Wright,C, Janetopoulos,C, Wikswo,JP. Mirrored Pyramidal Wells for Simultaneous Mutiple Vantage Point Microscopy, J. Microsc., 232, Pt.1, 1-6, 2008   DOI

Holcomb,MR, Bekele,RY, Lima,EA, Wikswo,JP. USB-Powered and -Controlled Isolated Constant-Current Physiological Stimulator, Rev. Sci. Instrum., 79, 126103 2008, PMCID: PMC2736648  DOI

Maleckar,MM, Woods,MC, Sidorov,VY, Holcomb,MR, Mashburn,DN, Wikswo,JP, Trayanova,NA. Polarity Reversal Lowers Activation Time During Diastolic Field Stimulation of the Rabbit Ventricles: Insights into Mechanisms, Am. J. Physiol. Heart, 295, H1626-H1633, 2008, PMCID: PMC2593523  DOI

Benninger,RKP, Zhang,M, Head,WS, Satin,LS, Piston,DW. Gap Junction Coupling and Calcium Waves in the Pancreatic Islet, Biophys. J., 95, 5048-5061, 2008   DOI

Hutson,MS, Brodland,GW, Yang,J, Viens,D. Cell Sorting in Three Dimensions: Topology, Fluctuations, and Fluidlike Instabilities, Phys. Rev. Lett., 101, 148105 2008   DOI

Hutson,MS. Physical Aspects of Developmental Biology: 21st Century Perspectives 'On Growth and Form' - Preface, Physical Biology, 5, E01 2008   DOI

Hutson,MS and Ma,XY. Mechanical Aspects of Developmental Biology: Perspectives On Growth and Form in the (Post)-Genomic Age, Physical Biology, 5, 015001 2008   DOI

Xiao,Y, Guo,M, Zhang,P, Shanmugam,G, Polavarapu,PL, Hutson,MS. Wavelength-Dependent Conformational Changes in Collagen After Mid-Infrared Laser Ablation of Cornea, Biophys. J., 94, 1359-1366, 2008   DOI

Werdich,AA, Lima,EA, Dzhura,I, Singh,MV, Li,J, Anderson,ME, Baudenbacher,FJ. Differential Effects of Phospholamban and Ca²⁺/Calmodulin-Dependent Kinase II on [Ca²⁺]_i Transients in Cardiac Myocytes at Physiological Stimulation Frequencies, Am. J. Physiol. Heart, 294, 2352-2362, 2008   DOI

Baudenbacher,F, Schober,T, Pinto,JR, Sidorov,VY, Hilliard,F, Solaro,RJ, Potter,JD, Knollmann,BC. Myofilament Ca2+ Sensitization Causes Susceptibility to Cardiac Arrhythmia in Mice, J. Clin. Invest., 118, 3893-3903, 2008  DOI

Weiss,BP, Fong,LE, Vali,H, Lima,EA, Baudenbacher,FJ. Paleointensity of the Ancient Martian Magnetic Field, Geophys. Res. Lett., 35, L23207 2008  DOI  

2007:

Addae-Mensah,KA, Kassebaum,NJ, Bowers,MJ, II, Reiserer,RS, Rosenthal,SJ, Moore,PE, Wikswo,JP, A Flexible, Quantum Dot-Labeled Cantilever Post Array for Studying Cellular Microforces, Sensors and Actuators A-Physical, 136: 385-397, 2007  DOI

Addae-Mensah,KA, Reiserer,RS, Wikswo,JP, Poly(Vinyl Alcohol) As a Structure Release Layer for Microfabrication of Polymer Composite Structures, J Micromech Microeng, 17: N41-N46, 2007  DOI

Bornhop,DJ, Latham,JC, Kussrow,A, Markov,DA, Jones,RD, Sorensen,HS , Free-Solution, Label-Free Molecular Interactions Studied by Back-Scattering Interferometry, Science, 317: 1732-1736, 2007  DOI

Ges,IA, Ivanov,BL, Werdich,AA, Baudenbacher,FJ, Differential pH Measurements of Metabolic Cellular Activity in Nl Culture Volumes Using Microfabricated Iridium Oxide Electrodes, Biosens Bioelectronics, 22: 1303-1310, 2007  DOI

Lipski,AM, Jacquiery,C, Choi,H, Eberli,D, Stevens,MM, Martin,I, Chen,I-W,  Shastri,VP, Nanoscale engineering of biomaterial surfaces, Advanced Materials, 19(4): 553-557, 2007  DOI

Hutson, MS and Ma, X , Plasma and Cavitation Dynamics during Pulsed Laser Microsurgery In Vivo, Phys Rev Lett, 99, 158104, 2007  DOI

Mishra,A, Lu,Y, Choe,AS, Aldroubi,A, Gore,JC, Anderson,AW, Ding,Z, An Image-Processing Toolset for Diffusion Tensor Tractography, Magn Reson Imaging, 25: 365-376, 2007  DOI

Sussman,E, Clarke,MB, Shastri,VP, A Single Step Process to Produce Surface-Functionalized Nanoparticles from Non-Functionalized Degradable Polymers, Langmuir, 23(24): 12275-12279, 2007  DOI

Vajandar,SK, Xu,D, Markov,D, Wikswo,JP, Hofmeister,W, Li,D, SiO₂-Coated Porous Anodic Alumina Membrane for Electroosmotic Pumping, Nanotechnology, 18,  275705, 2007  DOI

McLean,JA, Ridenour,WB, Caprioli,RM. Profiling and Imaging of Tissues by Imaging Ion Mobility-Mass Spectrometry, J. Mass Spectrom., 42, 1099-1105 (2007) 10.1002/jms.1254  DOI

Weiner,AA, Shuck,D, Bush,J, Shastri,VP, Optimization of photocrosslinked anhydride systems for bone augmentation applications: characterization of in vitro degradation, Biomaterials, 28: 5259-5270, 2007  DOI

Xu,X, Shastri,VP, A Modular Approach to the Synthesis of Property-Tunable Biodegradable Polyesters Derived from Poly(e-Caprolactone), Corrosion Engineering Science and Technology, 42(4): 293-299 (Invited Paper), 2007  DOI

Mashburn DN, Hinkson SJ, Woods MC, Gilligan JM, Holcomb MR, Wikswo JP, A High-Voltage Cardiac Stimulator for Field Shocks of a Whole Heart in a Bath, Review of Scientific Instruments, 78, 104302, 2007  DOI

Sidorov VY, Woods MC, Baudenbacher F., Cathodal Stimulation in the Recovery Phase of a Propagating Planar Wave in the Rabbit Heart Reveals Four Stimulation Mechanisms., J Physiol, 583(Pt 1):237-250, 2007, PMCID: PMC2277246  DOI

Werdich AA, Baudenbacher F, Dzhura I, Jeyakumar LH, Kannankeril PJ, Fleischer S, LeGrone A, Milatovic D, Aschner M, Strauss AW, Anderson ME, Exil VJ., Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice, Am J Physiol Heart Circ Physiol, 292(5):H2202-H2211, 2007  DOI

Edwards,GS, Pearlstein,RD, Copeland,ML, Hutson,MS, Latone,K, Spiro,A, Pasmanik,G. 6450 Nm Wavelength Tissue Ablation Using a Nanosecond Laser Based on Difference Frequency Mixing and Stimulated Raman Scattering, Opt. Lett., 32, 1426-1428, 2007   DOI

Peralta,XG, Toyama,Y, Hutson,MS, Montague,R, Venakides,S, Kiehart,DP, Edwards,GS. Upregulation of Forces and Morphogenic Asymmetries in Dorsal Closure During Drosophila Development, Biophys. J., 92, 2583-2596, 2007  DOI

Weiss,BP, Lima,EA, Fong,LE, Baudenbacher,FJ. Paleointensity of the Earth's Magnetic Field Using SQUID Microscopy, Earth and Planetary Science Letters, 264, 61-71, 2007  DOI  

2006:

Eklund,SE, Snider,RM, Wikswo,J, Baudenbacher,F, Prokop,A, Cliffel,DE, Multianalyte Microphysiometry as a Tool in Metabolomics and Systems Biology, J Electroanal Chem, 587: 333-339, 2006  DOI

Sai,JG, Walker,G, Wikswo,J, Richmond,A, The IL Sequence in the LLKIL Motif in CXCR2 is Required for Full Ligand Induced Activation of ERK, AKT and Chemotaxis in HL60 Cells, J Biol Chem, 281: 35931-35941, 2006  DOI

Shastri,VP, Future of regenerative medicine: Challenges and hurdles, Artificial Organs, 30(10):  828-834 (Invited Paper), 2006  DOI

Warnement,MR, Faley,SL, Wikswo,JP, Rosenthal,SJ, Quantum Dot Probes for Monitoring Dynamic Cellular Response:  Reporters of T Cell Activation, IEEE Trans Nanobiosci, 5: 268-272, 2006  DOI

Wikswo,JP, Prokop,A, Baudenbacher,F, Cliffel,D, Csukas,B, Velkovsky,M, The Engineering Challenges of BioNEMS: The Integration of Microfluidics, and Micro- and Nanodevices, Models, and External Control for Systems Biology, IEE Proceedings Nanobiotechnology, 153: 81-101, 2006  DOI  

Xu,XJ, Sy,JC, Shastri,VP , Towards developing surface eroding poly(alpha-hydroxy acids, Biomaterials, 27: 3021-3030, 2006  DOI

Gattacceca,J, Boustie,M, Weiss,BP, Rochette,P, Lima,EA, Fong,LE, Baudenbacher,FJ. Investigating Impact Demagnetization Through Laser Impacts and SQUID Microscopy, Geology, 34, 333-336, 2006  DOI

Huang,S and Wikswo,J, Dimensions of Systems Biology, Reviews of Physiology, Biochemistry and Pharmacology, Amara,SG, Bamberg,E, Gudermann,T, Hebert,SC, Jahn,R, Lederer,WJ, Lill,R, Miyajima,A, Offermanns,S, Eds, 81-104, 2006

Xiao,Y, Guo,M, Parker,K, Hutson,MS. Wavelength-Dependent Collagen Fragmentation During Mid-IR Laser Ablation, Biophys. J., 91, 1424-1432, 2006   DOI  

2005:

Ges,IA, Ivanov,BL, Schaffer,DK, Lima,EA, Werdich,AA, Baudenbacher,FJ, Thin-Film IrOx pH Microelectrode for Microfluidic-Based Microsystems, Biosensors & Bioelectronics, 21: 248-256, 2005  DOI

Fong,LE, Holzer,JR, McBride,KK, Lima,EA, Baudenbacher,F, Radparvar,M, High-Resolution Room-Temperature Sample Scanning Superconducting Quantum Interference Device Microscope Configurable for Geological and Biomagnetic Applications, Rev Sci Instrum , 76, 053703, 2005  DOI

Walker,GM, Sai,JG, Richmond,A, Stremler,MA, Chung,CY, Wikswo,JP, Effects of Flow and Diffusion on Chemotaxis Studies in a Microfabricated Gradient Generator, Lab on a Chip, 5: 611-618, 2005, PMCID: PMC2665275  DOI

Wang,W, Shor,LM, LeBoeuf,EJ, Wikswo,JP, Kosson,DS, Mobility of Protozoa Through Narrow Channels, Appl Environ Microbiol, 71: 4268-4637, 2005  DOI

Yang,Z, Shen,W, Rottman,JN, Wikswo,JP, Murray,KT, Rapid Stimulation Causes Electrical Remodeling in Cultured Atrial Myocytes, J Mol Cell Cardiol, 38: 299-308, 2005  DOI

Baudenbacher F, Fong LE, Thiel G, Wacke M, Jazbinsek V, Holzer JR, Stampfl A, Trontelj Z., Intracellular axial current in Chara corallina reflects the altered kinetics of ions in cytoplasm under the influence of light, Biophysical J, 88(1):690-697, 2005  DOI

Sidorov VY, Woods MC, Baudenbacher P, Baudenbacher F., Examination of Stimulation Mechanism and Strength-Interval Curve in Cardiac Tissue, Am J Physiol Heart Circ Physiol, 289(6):H2602-H615, 2005  DOI  

2004:

Werdich,A, Lima,EA, Ivanov,B, Ges,I, Wikswo,JP, Baudenbacher,FJ, A Microfluidic Device to Confine a Single Cardiac Myocyte in a Sub-Nanoliter Volume on Planar Microelectrodes for Extracellular Potential Recordings, Lab on a Chip, 4: 357-362, 2004  DOI

Chancellor,EB, Wikswo,JP, Baudenbacher,F, Radparvar,M, Osterman,D, Heat Conduction Calorimeter for Massively Parallel High Throughput Measurements with Picoliter Sample Volumes, Appl Phys Lett, 85: 2408-2410, 2004  DOI

Eklund,SE, Taylor,D, Kozlov,E, Prokop,A, Cliffel,DE, A Microphysiometer for Simultaneous Measurement of Changes in Extracellular Glucose, Lactate, Oxygen, and Acidification Rate, Anal Chem, 76: 519-527, 2004  DOI

Prokop,A, Prokop,Z, Schaffer,D, Kozlov,E, Wikswo,JP, Cliffel,D, Baudenbacher,F, NanoLiterBioReactor:  Long-Term Mammalian Cell Culture at Nanofabricated Scale, Biomed Microdevices, 6: 325-339, 2004  DOI

Rocheleau,JV, Walker,GM, Head,WS, McGuinness,OP, Piston,DW, Microfluidic Glucose Stimulation Reveals Limited Coordination of Intracellular Ca2+ Activity Oscillations in Pancreatic Islets, PNAS, 101:12899-12903, 2004  DOI

Holzer JR, Fong LE, Sidorov VY, Wikswo JP Jr, Baudenbacher F., High Resolution Magnetic Images of Planar Wave Fronts Reveal Bidomain Properties of Cardiac Tissue, Biophysical J, 87(6):4326-32, 2004, PMCID: PMC1304939  DOI

Eklund,S and Cliffel,DE. Synthesis and Catalytic Properties of Soluble Platinum Nanoparticles Protected by a Thiol Monolayer, Langmuir, 20, 6012-6018, 2004  DOI

2003:

Baudenbacher,F, Fong,LE, Holzer,JR, Radparvar,M, Monolithic Low-Transition-Temperature Superconducting Magnetometers for High Resolution Imaging Magnetic Fields of Room Temperature Samples, Appl Phys Lett, 82: 3487-3489, 2003   DOI

Eklund,SE, Cliffel,DE, Kozlov,E, Prokop,A, Wikswo,JP, Jr., Baudenbacher,FJ, Modification of the Cytosensor TM Microphysiometer to Simultaneously Measure Extracellular Acidification and Oxygen Consumption Rates, Anal Chim Acta, 496:93-101, 2003  93-101, 2003  DOI  

 Thematic Issues, Experimental Biology and Medicine

Thematic Issue: The Biology and Medicine of Microphysiological Systems, Wikswo JP, Editor, Exp. Biol. Med., 239 (September 2014)

Thematic Issue: Progress Toward Adoption of Microphysiological Systems in Biology and Medicine, Wikswo JP, Editor, Exp. Biol. Med., 242 (October and November 2017)

 Letters, Communications, Brief Reports & Commentaries

Hall A, Westlake G, Short BP, Pearson M, Ess KC, TSC1 Mosaicism leading to Subependymal Giant Cell Astrocytoma but not Tuberous Sclerosis Complex, Pediatr. Neurol., 123:38-39, 2021 PMCID: PMC8429189 DOI

Geerts H, Wikswo J, van der Graaf PH, Bai JPF, Gaiteri C, Bennett D, Swalley SE, Schuck E, Kaddurah-Daouk R, Tsaioun K, Pelleymounter MA, Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges, CPT:Pharmpacometrics Syst. Pharmacol., 9:5-20, 2020   DOI

Wathen C, Janigro D, IL-1β Associations with Posttraumatic Epilepsy Development: A Genetics and Biomarker Cohort Study, Epilepsia, 55:1313, 2014  PMCID: PMC4843779  DOI

Hummel S, Quaranta V, Wikswo JP, The Biohacker: A Threat to National Security, CTC Sentinel, 7:8-11, 2014  https://ctc.usma.edu/the-biohacker-a-threat-to-national-security/

Lee SH et al., ROS-Cleavable Proline Oligomer Crosslinking of Polycaprolactone for Pro-Angiogenic Host Response, J. Mater. Chem. B, 2:7109-7113, 2014 DOI

Gray,RA and Wikswo,JP. Several Small Shocks Beat One Big One, Nature, 475, 181-182, 2011  DOI

Enders JR, Goodwin CR, Marasco CC, Seale KT, Wikswo JP, McLean JA. Advanced Structural Mass Spectrometry for Systems Biology:  Pulling the Needles From Haystacks, LCGC and Spectroscopy Supp. 9(3), 18-23, 2011  Full Text 

Seale,K, Janetopoulos,C, Wikswo,J. Micro-Mirrors for Nanoscale Three-Dimensional Microscopy, ACS Nano, 3, 493-497, 2009   DOI

Phelan,VV et al. Adenylation Enzyme Characterization Using G-¹⁸O₄-ATP Pyrophosphate Exchange, Chemistry & Biology, 16, 473-478, 2009  DOI  

Gies,AP, Kliman,M, McLean,JA, Hercules,DM. Characterization of Branching in Aramid Polymers Studied by MALDI-Ion Mobility/Mass Spectrometry, Macromolecules, 41, 8299-8301 (2008)  DOI

Fenn,LS and McLean,JA. Enhanced Carbohydrate Structural Selectivity in Ion Mobility-Mass Spectrometry Analyses by Boronic Acid Derivatization, Chem. Commun., Issue 43, 5505-5507 (2008)  DOI

Methods Papers and Application Notes

Aisenbrey EA, Torr E, Johnson H, Soref C, Daly W, Murphy WL, A protocol for rapid pericyte differentiation of human induced pluripotent stem cells, STAR Protoc., 2:100261, 2021. PMCID: PMC7811164 DOI

Bowman A, Scherrer J, Reiserer R, Note: A Single-Chamber Tool for Plasma Activation and Surface Functionalization in Microfabrication, Rev. Sci. Instr., 86:066106, 2015.  PMCID: PMC4482809 DOI

Georgescu,W, Wikswo,JP, Quaranta,V. Cell Animation:  An Open Source MATLAB Framework for Microscopy Assays, Bioinformatics, 28, 138-139, 2012  DOI

Newaz,AKM et al. Graphene Transistor As a Probe for Streaming Potential, Nano Let., 12, 2931-2935, 2012  DOI

Markov,DA, Lillie,EM, Samson,PC, Wikswo,JP, McCawley,LJ. A Method for Periodic Sterile Sample Collection During Continuous Cell Culture in Microfluidic Devices, Lab Chip, Chips and Tips, 2010 Full Text

Greene,J, Henderson,JW, Jr., Wikswo,JP. Rapid and Precise Determination of Cellular Amino Acid Flux Rates Using HPLC With Automated Derivatization With Absorbance Detection. Application Note, 5990-3283EN, Agilent Technologies , 2009   Full Text  

Book Chapters

Roth BJ, Sidorov VY, Wikswo JP, Virtual Electrode Theory of Pacing, in Cardiac Bioelectric Therapy: Mechanisms and Practical Implications, 2nd edition, Efimov IR, Ng FS, Laughner JI, Eds., Springer Nature, Chapter 12, pp. 147-179 (2021) DOI

Taylor D, Gough A, Schurdak ME, Vernetti L, Chennubhotla CS, Lefever D, Pei F, Faeder J, Lezon T, Stern A, Bahar I, Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology, in Handbook of Experimental Pharmacology, Switzerland AG: Springer Nature (Epub June 15, 2019) DOI

Sai J, Rogers M, Hockemeyer K, Wikswo JP, Richmond A, Chapter Two - Study of Chemotaxis and Cell-Cell Interactions in Cancer with Microfluidic Devices, in Methods in Enzymology, M.H. Tracy, Ed., Academic Press, Vol. 570, pp. 19-45, 2016.  PMCID: PMC5378165 DOI

Nimjee SM, Grant GA, Winn HR, Janigro D, Blood-Brain Barrier, in Youmans and Winn Neurological Surgery, 7th Edition, H. Winn, Ed., Elsevier, Chapter 8 (2016)

Iffland PH, Song A, Prager B, Brennan C, Janigro D, Impact of Anesthesia on Blood-Brain Barrier Permeability, in Perioperative Neurosciences, E. Farag, E. Manno, M. Argalious, Eds., Nova Science Publishers, Chapter 17 (ebook, 2015)

Stow SM, Lareau NM, Hines KM, McNees CR, Goodwin CR, Bachmann BO, McLean JA, Structural Separations for Natural Product Characterization by Ion Mobility-Mass Spectrometry: Fundamental Theory to Emerging Applications, in Natural Products Analysis: Instrumentation, Methods, and Applications, V. Havlicek and J. Spizek, Eds., John Wiley & Sons Chapter 11 2014. DOI          

Janigro D, Walker MC, What Non-Neuronal Mechanisms Should Be Studied to Understand Epileptic Seizures? In: Scharfman H., Buckmaster P. (eds) Issues in Clinical Epileptology: A View from the Bench. Advances in Experimental Medicine and Biology, vol 813, pp. 253-264, Springer, Dordrecht, 2014.         PMCID: PMC4842021 DOI

Iffland PH, Grant GA, Janigro D, Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain Injury, in Vascular Mechanisms in CNS Trauma, Eng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen, Eds., Springer Series in Translational Stroke Research, Vol. 5, pp. 29-45, 2014   doi: 10.1007/978-1-4614-8690-9_2

McKenzie JR, Cliffel DE, Wikswo JP, Electrochemical Monitoring of Cellular Metabolism, in Encyclopedia of Applied Electrochemistry, Savinell,R Ota,K, and Kreysa,G, Eds., Springer-Verlag Heidelberg, 2014 DOI

Fenn,LS and McLean,JA. Structural separations by Ion Mobility-MS for Glycomics and Glycoproteomics. In: Mass spectrometry of glycoproteins: methods and protocols, Methods in molecular biology, Kohler,J and Patrie,SM, eds. Humana Press, New York, 171-193, 2013   DOI

May,JC, Goodwin,CR, McLean,JA. Gas-Phase Ion Mobility-Mass Spectrometry (IM-MS) and Tandem IM-MS/MS Strategies for Metabolism Studies and Metabolomics. In: Encyclopedia of drug metabolism and interactions, Lyubimov,AV, ed. Wiley, Hoboken, N.J., 1-29, 2012   DOI

Hines,KM, Enders,JR, McLean,JA. Multidimensional Separations by Ion Mobility-Mass Spectrometry. In: Encyclopedia of Analytical Chemistry (on-line), Myers,RA and Muddiman,D, eds. John Wiley & Sons, Ltd, 2012   DOI

Schmidt,M and  Lipson,H. Age-Fitness Pareto Optimization. In: Genetic programming theory and practice VIII, Riolo,R, McCongahy,T, Vladislavleva,E, eds. Springer, New York, 129-146, 2011   DOI

Enders,JR, Kliman,M, Sundarapandian,S, McLean,JA. Peptide and Protein Analysis Using Ion Mobility-Mass Spectrometry. In: Peptide and Protein Mass Spectrometry in Drug Discovery, Gross,ML, Chen,G, Pramanik,B, eds. J. Wiley & Sons, 139-174, 2011  DOI

McLean,JA, Schultz,JA, Woods,AS. Ion Mobility-Mass Spectrometry for Biological and Structural Mass Spectrometry. In: Electrospray and MALDI mass spectrometry: fundamentals, instrumentation, practicalities, and biological applications, Cole,RB, ed. Wiley, Hoboken, N.J., 411-439, 2010

May,JC and McLean,JA. The Conformational Landscape of Biomolecules in Ion Mobility-Mass Spectrometry. In: Ion Mobility Spectrometry-mass Spectrometry: Theory and applications, Wilkins,CL and Trimpin,S, eds. CRC Press, Boca Raton, FL, 327-343, 2010

McLean,JA, Fenn,LS, Enders,JR. Structurally Selective Imaging Mass Spectrometry by Imaging Ion Mobility-Mass Spectrometry. In: Mass Spectrometric Imaging:  History, Fundamentals and Protocols, Sweedler,JV and Rubakhin,SS, eds. Humana Press, New York, 363-383, 2010  DOI

Wikswo,JP and Roth,BJ. Virtual Electrode Theory of Pacing. In: Cardiac bioelectric therapy:  Mechanisms and practical implications, Efimov,I, Kroll,M, Tchou,P, eds. Springer,  283-330, 2009   DOI

Rocheleau,JV and Piston,DW. Combining Microfluidics and Quantitative Fluorescence Microscopy to Examine Pancreatic Islet Molecular Physiology. In: Methods in Cell Biology, Correia,JJ and Detrich,HW, eds. Elsevier,  71-92, 2008  DOI

Jayagopal,A,  Shastri,VP, Nanoengineering of Drug Delivery Systems, in Nanoparticulate Drug Delivery Systems, Thassu,D, Deleers,M, Pathak,Y, Eds., Informa Heathcare, NY,  Chp. 7, 99-110, 2007

Jayagopal,A,  Shastri,VP, Nanoscale Engineering of Biomaterial Surfaces, in Nanotechnologies for the Life Sciences, Volume 8: Nanotechnologies for Tissue, Cell and Organ Engineering, Kumar,C, Ed., Wiley-VCH , Chapter 12, 461-505, 2006  DOI

Eklund,SE, Kozlov,E, Taylor,DE, Baudenbacher,F, Cliffel,DE, Real-Time Cell Dynamics With a Multianalyte Physiometer, in NanoBiotechnology Protocols, Rosenthal,S and Wright,D, eds. Humana Press, Totawa, NJ, 209-223, 2005  DOI