A book edited by renown invertebrate immunologist Dr. Kenneth Söderhäll was published today.  As an invited contributing author, Julián Hillyer published a chapter in this book describing the  immune response mounted by mosquitoes in response to infection.  Specifically, the chapter describes the biology of pathogens inside mosquitoes, mosquito compartments and barriers to infection, and the molecular basis of mosquito immunity.

CITATION:

Hillyer, J.F. 2010. Mosquito immunity. Invertebrate Immunity. 708:218-238.

ISBN: 978-1-4419-8058-8.

Publication date: December 20, 2010.

1. •Available online through Landes Bioscience through THIS link.  For a pdf copy, click HERE.  Otherwise you can email me by clicking HERE.
   

CHAPTER ABSTRACT:

Throughout their lifetime, mosquitoes are exposed to pathogens during feeding, through breaks in their cuticle and following pathogen‐driven cuticular degradation. To resist infection, mosquitoes mount innate cellular and humoral immune responses that are elicited within minutes of exposure and can lead to pathogen death via three broadly defined mechanisms: lysis, melanization and hemocyte‐mediated phagocytosis. This chapter reviews our current understanding of the mosquito immune system, with an emphasis on the physical barriers that prevent pathogens from entering the body, the organs and tissues that regulate immune responses and the mechanistic and molecular bases of immunity.

About the book:

• Describes the diversity between different invertebrate animal groups.

1. •Shows that the prophenoloxidase activating system and the induction of the Toll pathway in an insect share the same proteolytic cascade.
   

2. •Reflects the growing interest in invertebrate immunity, which is the study of the link between physiology and immunity.
   

Table of contents:

1. 1.Cnidarian Immunity: A Tale of Two Barriers
   René Augustin and Thomas C.G. Bosch
   

2. 2.Gastropod Immunobiology
   Eric S. Loker
   

3. 3.Bivalve Immunity
   Linsheng Song, Lingling Wang, Limei Qiu and Huan Zhang
   

4. 4.Earthworm Immunity
   Martin Bilej, Petra Procházková, Marcela Šilerová and Radka Josková
   

5. 5.Leech Immunity: From Brain to Peripheral Responses
   Aurélie Tasiemski and Michel Salzet
   

6. 6.Innate Immunity in C. Elegans
   Ilka Engelmann and Nathalie Pujol
   

7. 7.Immunocompetent Molecules and Their Response Network in Horseshoe Crabs
   Shun‑ichiro Kawabata
   

8. 8.Tick Innate Immunity
   Petr Kopáček, Ondřej Hajdušek, Veronika Burešová and Sirlei Daffre
   

9. 9.Beetle Immunity
   Ji‑Won Park, Chan‑Hee Kim, Jiang Rui, Keun‑Hwa Park, Kyung‑Hwa Ryu,
   Jun‑Ho Chai, Hyun‑Ok Hwang, Kenji Kurokawa, Nam‑Chul Ha,
   Irene Söderhäll, Kenneth Söderhäll and Bok Luel Lee
   

10. 10.Immunity in Lepidopteran Insects
    Haobo Jiang, Andreas Vilcinskas and Michael R. Kanost
    

11. 11.Fly Immunity: Recognition of Pathogens and Induction of Immune Responses
    Shoichiro Kurata
    

12. 12.Mosquito Immunity
    Julián F. Hillyer
    

13. 13.Crustacean Immunity
    Lage Cerenius, Pikul Jiravanichpaisal, Hai‑peng Liu and Irene Söderhäll
    

14. 14.Echinoderm Immunity
    L. Courtney Smith, Julie Ghosh, Katherine M. Buckley, Lori A. Clow,
    Nolwenn M. Dheilly, Tor Haug, John H. Henson, Chun Li, Cheng Man Lun,
    Audrey J. Majeske, Valeria Matranga, Sham V. Nair, Jonathan P. Rast,
    David A. Raftos, Mattias Roth, Sandro Sacchi, Catherine S. Schrankel
    and Klara Stensvåg
    

15. 15.Urochordate Immunity
    Masaru Nonaka and Honoo Satake