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Cores Facilities

VU Cores:

  • ACCRE – Advanced Computing Center for Research and Education

    The Advanced Computing Center for Research and Education is comprised of High Performance Computing services that provide an environment for a wide variety of research projects across Vanderbilt. These services include: High Performance Computing *** Non-cluster Tape Backup Services Logistical Storage (L-Store) The Research and Education Data Depot Network (REDDnet)

    Director:  Carie Lee Kennedy


  • Biochemistry Tissue Core

    Biochemistry is the field of study of the chemical basis of biological processes. As research develops, the field uses new tools and approaches to address problems in more detail. 

    Core Manager: Kimberly Johnson


  • Biomedical Illustration (BMI) Core

    The Biomedical Illustration (BMI) Core is the bridge between science and art. It is the vehicle for communicating data and generating interest in research. This Core engages the scientific community and the general public by making data and research tangible and accessible with beautiful visualizations. Deliverables and Projects created by the Core include various forms of art work and communication materials for VU and VUMC researchers. Illustrations visualizing any biological process or scientific data including: data figures (charts, graphs, etc.), data interpretation, anatomical illustrations, editorial illustrations, journal covers, and instructional illustrations (lab manuals, educational materials for medical students, etc.)  3-D Models to bring any protein, molecule, or anatomy to life . Including representations of proteins, molecular illustrations, anatomical models, and engagement with these models via apps and animation. Animations to set scientific research in motion. Including 2-D and 3-D animations of molecular processes and cellular biology and instructional animations of research topics.   Websites to access and engage with research world-wide.Including curated content that will educate the general public about current research and generate interest in furthering that research. Logos and Branding to create an individual identity for a lab or research group that summarizes and promotes their research, in the interest of generating more grant support and furthering that research. Creative Consultation Services for clients to bring in visuals they are creating/have created and BMI will provide creative consultation on how to improve and/or provide added visuals. The can have a comprehensive Project Review that can include suggestions from the BMI and book time for work created by an Illustrator. No matter your visualization project, we can help.

    Core Manager: Rachel Chandler


  • Bret Poster Printing Service

    The BRET Office of Postdoctoral Affairs (OPA) assists postdoctoral fellows during their training at Vanderbilt University Medical Center (VUMC). Our office makes postdoctoral appointments and reappointments. We meet with postdoctoral candidates upon faculty request and with new postdoctoral fellows focusing on the Compact Between Postdoctoral Appointees and their MentorsIndividual Development Plan and resources available, including resources to aid postdocs in developing writing and presentation skills.  The BRET Office of Postdoctoral Affairs sponsors the Vanderbilt Postdoctoral Association which welcomes all Vanderbilt postdoctoral fellows from all schools to PDA events such as;the PDA and Shared Resources Poster Symposium and Research Day, monthly meetings, holiday events and celebration ofNational Postdoc Appreciation Weekwith the Postdoc Family Picnic.The Scientist'sannual survey has consistently ranked Vanderbilt as one of the best places for postdocs to work in the United States. Whether you are a prospective postdoctoral fellow considering a move to Nashville or a current postdoctoral fellow seeking assistance, we are here to offer our support.

    Core Manager: Karen Perry


  • Cancer & Immunology Core (CIC)

    The Cancer & Immunology Core (CIC) provides access to mass cytometry and other advanced cytometry services for cancer and immunology research. The CIC uses well-established reagent sets and protocols to help researchers get a first mass cytometry figure or to carry out studies in areas where the technology development has been robust, such as monitoring human T cell subsets.

    Core Manager:  Hannah Polikowsky

    Scientific Director:  Jonathan Irish, Ph.D.


  • Cell & Development Biology

    In the Department of Cell and Developmental Biology, a diverse group of disciplines and technologies have been merged together to reflect a common interest in discovering how cells function, both alone and in the context of a multi- cellular organism. Some researchers in the department study how specific molecules function in cells. Others study how subcellular machines composed of assemblies of molecules operate. Still others study communication between cells and how groups of cells specify more complex systems such as tissues and organs. Researchers in the department employ a wide range of instruments and methods including live cell imaging, electron microscopy, structural biology, cell culture, animal models, proteomics, and genetics.

    They also use an array of model organisms to study questions of common interest ranging from the single celledyeast, to frogs, flies, zebrafish, and mice. By building bridges between researchers working on cellular functions at all levels, the department has developed an interactive and exciting environment for graduate student training.

    Cell & Developmental Biology Equipment Resource

    Core Manager: Anthony Tharp
    E-Mail: Anthony


  • Cell Imaging Shared Resource (CISR)

    Supports the full range of modern microscopy and digital imaging capabilities in order to enable and accelerate research that would otherwise be reduced in quantity and quality. Currently over 200 research groups use the facilities and services of the Resource, which maintains an active development program to keep the instrumentation and systems current, functional, accessible, and easy to use. CISR currently provides facilities for both optical and electron microscopy; there are six confocal microscopes, one line-scanning microscope, two 2-photon-excitation microscopes, and four advanced wide-field microscopes as well as a Phillips CM-12 120keV Transmission Electron microscope system. The laboratory is fully equipped to carry out numerous aspects of "routine" as well as specialized electron microscopy. Included in the specialized services available through the resource are: 1) preparative techniques, such as embedding and sectioning, critical point drying, high-resolution low angle and rotary shadowing, and cryo-EM; 2) research techniques, such as immuno- and enzyme-cytochemistry, autoradiography, and whole-mount microscopy; and 3) analytical techniques, such as on- and off-line microcomputer based systems for image processing, pattern analysis, and 3-D reconstruction.

    Scientific Director: Matt Tyska

    Director: Jenny Schafer

    Co-Director – Electron Microscopy: Jay Jerome


    Faculty Advisory Committee Memebers (2012-2013):
    Elisabeth Dykens (Kennedy Center)
    Jim Goldenring (Surgical Sciences)
    Scott Hiebert (Cancer Center)
    David Kosson (Civil and Environmental Engineering)
    Mark Magnuson (Stem Cell Biology)
    Richard Peek (Digestive Disease Research Center)
    Al Powers (Diabetes Center)
    Jeffrey Schall (Vision Research Center)
    David Wasserman (Mouse Metabolic Phenotyping Center)
    Chris Wright (Program in Developmental Biology)

  • Center for Innovative Technology (CIT)

    The Vanderbilt Center for Innovative Technology (CIT) recharge center will be an analytical facility specializing in a range of cutting edge mass spectrometry (MS) and confocal microscopy techniques. The center will provide the infrastructure and expertise to measure both targeted and broad spectrum untargeted molecules derived from biospecimens (cells, tissues, fluids, etc). There will be an emphasis on the use and development of technologies including ion mobility MS, for analyses of diverse samples ranging from basic cell culture models to effluent of advanced systems such as organ-on-chip microfluidic or 3-dimensional devices. 

    Core Manager: Heather Watkins

    Core Associate: Stacy Sherrod

    iLab Landing Page

  • Center for Structural Biology

    CSB Computing Service Center


    CSB Biophysical Instrumentation

    CSB MegaLab

    CSB Modeling

    Core Manager:  Lisa Wright

  • Chemistry

    Chemistry Storeroom

    Chemistry XRD

    Core Manager:  Catherine McRen

    Core Manager: Magdalena Paszewsk

  • Distributed Online Research Storage (DORS)

    A new disk storage device called DORS is now mounted on ACCRE via collaboration between the Center for Structural Biology, the VUMC Office of Research, VUIT and ACCRE.

    Director: Jarrod Smith, Ph.D.
    E-Mail: jarrod.smith@Vanderbilt.Edu
    Phone: (615) 554-5681

  • ISDE Radiation Effects Laboratory

    Director: Robert Reed 

    E-Mail: robert.reed@Vanderbilt.Edu
    Phone: 615-343-2702

  • MSRC - Mass Spectrometry Research Center

    Provides instrumentation for structural analysis of biological molecules and qualitative and quantitative assays of chemotherapeutic agents and metabolites in physiological fluids. The instrumentation facilities consist of a variety of mass spectrometric and high-pressure liquid chromatographic systems.

    Learn more about MSRC's core capabilities, educational opportunities, and current research: Watch the video.

    Mass Spectrometry Core

    Provides instrumentation for structural analysis of biological molecules and qualitative and quantitative assays of chemotherapeutic agents and metabolites in physiological fluids. The instrumentation facilities consist of a variety of mass spectrometric and high-pressure liquid chromatographic systems.

    Director: Kevin Schey
    Assistant Director: Wade Calcutt
    E-Mail: wade.calcutt@Vanderbilt.Edu

    Faculty Advisory Committee Members (2012-2013):
    Michael Aschner (Molecular Toxicology)
    Alan Brash (Clinical Pharmacology) 
    Roger Colbran (Molecular Physiology and Biophysics) 
    Sean Davis (Clinical Pharmacology) 
    Fred Guengerich (Biochemistry) 
    Scott Hiebert (VICC) 
    Larry Marnett (VICB) 
    Claus Schneider (Clinical Pharmacology) 
    Eric Skaar (Pathology, Microbiology and Immunology) 

     Proteomics Core

    Provides state-of-the-art instrumentation and expertise in analytical proteomics, proteome profiling, and imaging to Vanderbilt researchers. Instrumentation is available for protein and peptide separations by 2D-gel electrophoresis and multidimensional high performance liquid chromatography (LC).

    Proteins and peptides of interest are processed and subjected to mass spectral (MS) analysis, and protein identifications are made based on a comparison of MS data with sequence information from genomic, protein, and EST databases. Proteome profiling and imaging in frozen tissue sections are done by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) MS. Proteomics Laboratory staff provide consultation on experimental design and sample preparation.

    Director: Kevin Schey

    Co-Associate Director: Hayes McDonald



    Tissue/Serum Proteomics Core Director: Richard Caprioli

    Faculty Advisory Committee Members (2012-2013):
    Roger Colbran (Molecular Physiology and Biophysics)
    David Cortez (Biochemistry)
    Timothy Cover (Infectious Disease)
    Scott Hiebert (Cancer Center)
    Andrew Link (Pathology, Microbiology and Immunology)
    Larry Marnett (Institute for Chemical Biology)
    Richard Peek (Digestive Disease Research Center )


    Tissue/Serum Proteomics Core

    Offers a variety of services in order to determine the proteomic profiles of tissue, serum, and other biological fluids using MALDI mass spectrometry. Investigators work closely with Core personnel in order to design the experiment that will best answer the scientific questions being posed. The typical study involves examining protein changes between two experimental groups; e.g., control vs. diseased or treated vs. nontreated. The services offered by the Tissue/Serum Proteomics Core include tissue profiling, tissue imaging, 1D and 2D robotic biofluid fractionation and protein profiling, and multidimensional LC-MS/MS “shotgun” proteomics analysis of biofluids and tissue homogenates. In addition, various biocomputational services are offered in conjunction with data acquisition, including biostatistical comparisons of sample groups and image processing.

    Director: Richard Caprioli

  • Mouse Metabolic Phenotyping Center (MMPC)

    The Mouse Metabolic Phenotyping Center provides investigators wishing to address hypotheses related to diabetes and metabolism with a range of animal model systems. Assistance with mouse experimentation falls under the auspices of the Mouse Metabolic Phenotyping Center, which branched off from this core in 2001. Expertise of core personnel reflects the need to assist in both small and large animal experiments. Services provided are surgical, experimental, with limited analytical capacity (blood glucose, serology). Emphasis is on procedures needed to study conscious, unrestrained animals. Equipment available to investigators includes infusion pumps, blood flow meters, blood pressure monitors, gas analyzers, centrifuges, and glucose analyzers. The Animal Resources Core is experienced in developing new procedures and animal models to accommodate evolving research needs. Many of the procedures conducted in this core are novel. For this reason, training of investigators is an important responsibility of the Animal Resources Core.

    Director: David Wasserman
    E-mail: Website:

  • Vanderbilt Brain Institute (VBI)

    Neurochemistry Core Laboratory

    Offers services for neurochemical profiling of brain, peripheral tissues and body fluids. The core provides analytical services for the quantitation of multiple biogenic amine neurotransmitters (e.g. dopamine, norepinephrine, serotonin, acetylcholine), biogenic amine metabolites, amino acids and amino acid neurotransmitters (e.g. glutamate, GABA). Investigators provide primary tissue samples or extracts stabilized for analysis.

    Core Director: Ginger Milne
    Phone: (615) 936-5611

    Rat and Mouse Neurobehavior Cores

    This facility provides infrastructure and guidance to support the assessment of behavior in genetically altered mice. Automated, computer-controlled instrumentation provides for assessment of motor and cognitive behavior as well as drug responses. MNL core personnel consult with investigators on experimental design and train core users in animal handling, data acquisition, and statistical analysis. Core personnel may also assist with writing methods and results sections for manuscripts or grants.

    Murine Neurobehavioral Laboratory

    This facility provides infrastructure and guidance to support the assessment of behavior in genetically altered mice. Automated, computer-controlled instrumentation provides for assessment of motor and cognitive behavior as well as drug responses. MNL core personnel consult with investigators on experimental design and train core users in animal handling, data acquisition, and statistical analysis. Core personnel may also assist with writing methods and results sections for manuscripts or grants.

    Manager: John Allison
    Phone: (615) 322-0794

    Provides equipment, training and consulting for Vanderbilt personnel who are interested in studying rat models of both neurological and psychiatric disorders. Examples of assays available for research in rats include models of anxiety, depression, drug abuse, learning and memory, cognition, attention, social interaction, pain, motor activity and coordination. Investigators can employ the latest technology in video capture and software-based analysis of behavior.

    Rat Neurobehavioral Laboratory

    Provides equipment, training and consulting for Vanderbilt personnel who are interested in studying rat models of both neurological and psychiatric disorders. Examples of assays available for research in rats include models of anxiety, depression, drug abuse, learning and memory, cognition, attention, social interaction, pain, motor activity and coordination. Investigators can employ the latest technology in video capture and software-based analysis of behavior.

    Contact: Carrie Jones or Lisa Wright
    E-Mail: or
    Phone: (615) 343-4337

  • Vanderbilt Center for Stem Cell Biology (VCSCB)


    The Vanderbilt Center for Stem Cell Biology aims to understand the biology of stem cells and the mechanisms for directing their differentiation to specific cell fates.

    VCSCB Creative Data Solutions

    Creative Data Solutions is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.

    We provide a wide array of services that are essential to support these goals.

                  Director: Jean-Philippe Cartailler

                  E-Mail:  jp.cartailler@Vanderbilt.Edu


    VCSCB Transgenic Mouse/Embryonic Stem Cell Shared Resource

    The Transgenic Mouse / ES Cell Shared Resource assists investigators in generating, maintaining and storing germline-altered mice. This resource, which has been in existence for over 22 years, has generated over 2600 transgenic founder mice from 700 different DNA constructs and 5000 chimeric mice from over 800 different mouse ES cell clones. Prior to the discovery of the CRISPR/Cas system, the TMESCSR generated over 160 different gene-targeted mice. Since 2013, the TMESCSR has generated over 275 mutant pups by CRISPR/Cas injections from over 70 different projects.

                 Director: Mark Magnuson

                E-Mail: Mark.Magnuson@Vanderbilt.Edu

                Manager: Jennifer Skelton

                E-Mail: Jennifer.Skelton@Vanderbilt.Edu


  • Vanderbilt Institute of Chemical Biology (VICB)

    VICB research spans a broad range of interests and is characterized by interdisciplinary and cross-disciplinary approaches. Many VICB members have affiliations with other key institutes and centers at Vanderbilt, including the Vanderbilt Ingram Cancer Center (VICC), the Institute of Imaging Science (VUIIS), the Center for Structural Biology (CSB), the Mass Spectrometry Research Center (MSRC) and the Institute of Nanoscale Science and Engineering (VINSE). All investigators have access to VICB core facilities that provide chemical synthesis, high throughput screening, antibody production, and small molecule NMR services.

    Director: Gary Sulikowski


    Vanderbilt Antibody and Protein Resource  
    Paige Vinson  
    (615) 322-5623  

    VICB Chemical Synthesis Core
    Scientific Director: Gary Sulikowski
    E-Mail: gary.a.sulikowski@vanderbilt.Edu
    Assistant Director: Kwangho Kim
    Phone: (615) 322-7324

    VICB High-Throughput Screening Core
    Scientific Director: David Weaver 
    Director: Paige Vinson
    Phone: (615) 322-0342 

    VICB Small Molecule NMR Facility
    Director: Don Stec
    E -Mail: 
    Phone: (615) 322-6704 

  • Vanderbilt Insitute for Digital Learning (VIDL)

    The Vanderbilt Institute for Digital Learning (VIDL) is charged by the Chancellor and the Provost to

    • facilitate means by which on-campus education and learning are enhanced through online and other digital technology;
    • promote research at Vanderbilt on digitally-enhanced education and learning;
    • encourage and oversee world and local community service by Vanderbilt that involve digital learning, to include production and management of Vanderbilt’s massive, open, online courses (MOOCs); and
    • promotes sharing of resources (knowledge, human, infrastructure, best practices) on digital learning, to include an advisory role in online degree programs.

    VIDL Instructional Design

    VIDL Project Management

    VIDL Studio

    VIDL Videographer

    Core Manager:  Gayathri Narasimham


  • Vanderbilt Institute for Integrative Biosystems Research and Education (VIIBRE)

    VIIBRE, the Vanderbilt Institute for Integrative 
    Biosystems   Research and Education, was created in 2001 with a $5 million, five-year grant from the Vanderbilt Academic Venture Capital Fund to foster and enhance interdisciplinary research in innovative systems biology and systems engineering at Vanderbilt, integrated with a strong focus on undergraduate, graduate, and postdoctoral education.

    VIIBRE's mission is to invent the tools and develop the skills that are required to conduct research in systems biology - in other words, to elucidate the multitude of intracellular metabolic and signaling control mechanisms by which biological systems regulate homeostasis, differentiation, development, growth, repair, and responses to physiological and environmental stimuli. Control of cellular function is ubiquitous among living systems and occurs over spatiotemporal scales that range from rapid local control of transient molecular signaling events to slower regulatory mechanisms governing biological activity throughout an entire organism over its lifespan. This spatiotemporal breadth presents measurement and modeling challenges that require a coordinated, collaborative effort by scientists, engineers, and physicians whose expertise spans multiple disciplines.

    Taking advantage of Vanderbilt's existing strengths in science, medicine, engineering, and education, VIIBRE has instituted a broad program in  BioMicroElectroMechanical systems ( BioMEMS ) and advanced analytical and optical instrumentation and software to address pressing questions in systems biology. VIIBRE's activities are carried out in on- and off-campus collaborations in research areas such as cellular biosensors, bioprocess controllers, mathematical models for wound healing and cancer, infectious disease detection, biomedical imaging, and cellular/tissue engineering. One of VIIBRE's long-term challenges is to design and build hybrid silicon/biological systems (microfluidic cell habitats) that propose and generate models and conduct experiments on themselves to identify the principles (represented by mathematical equations) that describe cellular metabolic and signaling dynamics.

    To date, VIIBRE has helped bring to Vanderbilt over $70 million of new external funding. VIIBRE is now primarily funded by external grants and contracts.

    VIIBRE Automated Micro-Organ Systen

    VIIBRE Microfabrication Core

    Core Manager:  Sarazen Haile


  • Vanderbilt Institute of Nanoscale Science and Engineering (VINSE)

    Welcome to the website of the Vanderbilt Institute of Nanoscale Science and Engineering –– VINSE!

    VINSE is comprised of 45 faculty members from the College of Arts and Science, the School of Engineering, and the School of Medicine.  Created in 2001 with Academic Venture Capital Fund support from Vanderbilt’s endowment, VINSE hit the ground running by quickly building a small suite of laboratories for nanofabrication and nanocharacterization and working cooperatively with many departments to hire a cadre of nanoscience-oriented faculty.  Our primary research areas include nanobio/nanomedicine, nano-energy, nanoscale optics, computational nanoscience, and new nanoscale materials.  We have built graduate, undergraduate, and outreach educational programs while growing our faculty and adding additional experimental capabilities.  VINSE faculty now span 13 academic departments; our graduate educational arm is the Interdisciplinary Program in Materials Science; our undergraduate program is the Minor in Nanoscience and Nanotechnology; we organize classroom visitation and on-site High School Field Trip outreach programs; and we are building an expanded suite of core facilities in the new Engineering and Science Building. 

    Every single day, VINSE faculty, staff and students stretch the boundaries of nanoscience to advance our research, education, and outreach missions while fully embracing Vanderbilt University’s values of equality, collegiality, compassion and excellence in all endeavors.

    VINSE Cleanroom



    VINSE Nanocrystal Laboratory


    VINSE Osiris TEM 

    VINSE XPS Center

    Core Manager: Alisha McCord


VUMC Cores:

  • VUMC Biostatistics Collaboration Center

    Provides, enhances, and/or facilitates statistical collaborations involving the design, conduct, analysis or publication of biomedical research at the university. The BCC is comprised of biostatisticians and computer systems analysts from the Department of Biostatistics who are available to work with faculty on a variety of projects. They offer a wide range of highly trained experts with unique expertise for almost any collaboration. The BCC has considerable expertise in the design, conduct, and analysis of large scale clinical trials and research design for basic biomedical research. Varying levels of expertise are also available for consultation, from bachelor’s and master’s level trained biostatisticians and computer systems analysts to full professors.

    Biostatistics Collaboration Center Manager: Seth Martin

  • VUMC BioVU Vanderbilt DNA Databank

    Provides enabling resource for exploration of the relationships among genetic variation, disease susceptibility, and variable drug responses, and represents a key first step in moving the emerging sciences of genomics and pharmacogenomics from research tools to clinical practice.  A major goal of the resource is to generate datasets that incorporate de-identified information derived from medical records and genotype information to identify factors that affect disease susceptibility, disease progression, and/or drug response.

    Manager: Erica Bowton
    Core Contact:   Jonathan Fleming, PH.D
    Phone: (615)322-4810 

    Website: password required).

  • VUMC Center for Quantitative Sciences

    Provides consultative services for VICC investigators in the statistical design, conduct, and analysis of studies; collaborates in funded research efforts initiated by VICC laboratory and clinical investigators, by providing statistical expertise in study design, power and sample size analysis; data analysis; interpretation of results; and writing of manuscripts; provides relational database design, data tracking, forms, queries, and reports for investigator-initiated clinical trial databases or laboratory study databases; and develops and evaluate statistical methods for experimental design and data analysis.

    Contact: Lynne Berry for more information.
    E-Mail: lynne.d.berry@Vanderbilt.Edu

  • VUMC Clinical Research Center (CRC)

    The purpose of the Vanderbilt Clinical Research Center is to provide the resources needed by clinical and translational investigators to carry out their research in an environment optimized for safety, comfort and convenience of the patient or volunteer, with the facilities and expertise to provide the most advantageous milieu in which to address the investigator's experimental requirements. This includes outpatient space, inpatient beds, laboratories, equipment and supplies for clinical research by the faculty of Vanderbilt University, Meharry Medical College, and their collaborating investigators. The use of the center is justified on the basis of the quality and significance of the research and the special need for the Center's facilities.

    In the process of achieving its primary objective, the Clinical Research Center can also serve as a resource for teaching medical, graduate, and other multidisciplinary students, a site for research on the methodology of patient care systems, and an unique environment for the apprenticeship of young clinical investigators. The center is a component of the Vanderbilt Institute of Clinical and Translational Research (VICTR) organized under a Clinical and Translational Award (CTSA) made in 2007 by the National Center for Research Resources and the National Institute of Health.

    Program Manager: Jennifer Adams
    Phone: (615) 343-3655

  • VUMC Digital Histology Shared Resource

    The Digital Histology Shared Resource provides large-scale digital archiving and quantitative analysis of histological, immunocytochemical and immunofluorescence staining for tissue sections and tissue microarrays. The Ariol SL-50 automated scanning microscope and the Leica SCN400 Slide Scanner deliver solutions for high-resolution imaging in both bright field and fluorescence. Both instruments have high-capacity robotic autoloading (50 slides for the Ariol SL-50 and 384 slides for the Leica SCN400) making them ideal for large slide cohorts and tissue microarrays. The Leica SCN400 scanner can image normal size as well as large format slides and whole mounts. The associated software packages provide complex algorithms for unbiased, automated image analysis and quantitation of immunostaining in both bright field and fluorescence. In addition, these systems can be utilized as a permanent high-resolution solution for those who need archiving of histological material. The DHSR hosts a convenient, web-based digital slide-viewing environment (Digital Image Hub) for the rapid retrieval, review and annotation of scanned material. This easy to use digital slide box allows researchers to share images among colleagues, both at Vanderbilt and at other institutions, from any web browser while remaining in a digitally secure environment. Built-in conferencing features allow investigators to coordinate multi-site discussions of histological samples.

    The DHSR also supports shared usage of a Applied Precision/GE Deltavision Deconvolution Fluorescence microscope equipped with a Weatherstation for extended live cell imaging. The DHSR also houses an Optronix Digital Colony Counter for automated counting and size quantitation of cell colonies grown in multiple culture formats.

    Scientific Director: James R. Goldenring, M.D., Ph.D.
    Managing Director: Joseph Roland, Ph.D.

  • VUMC Division of Animal Care

    The Division of Animal Care (DAC) is the service core of the Office of Research that provides procurement, husbandry, and healthcare for experimental animals, as well as scientific/technical support for VU researchers.

    Our mission is to provide humane animal care that meets the highest national standards supporting knowledge and discovery through research. To that end, the DAC endeavors to provide excellent animal care and customer service in support of Vanderbilt’s research and teaching programs.

    Office hours are 7:30am-4:30pm Monday-Friday.

    For weekend, holiday and after-hours emergencies, contact the DAC by calling the numbers posted near the phones located in each facility or dialing 615.322.2231 and listening to the message to identify the appropriate individual to call.

    Website: - (VUnet password required.)

  • VUMC Flow Cytometry Shared Resource

    Provides flow cytometry services to faculty, staff, and students in the VUMC and to other investigators on a fee-for-service basis. The staff Maintains all instruments and provides the following services: Data acquisition, both by facility staff and qualified users, sorting, instruction in performing data analysis, instruction on instrument user (analytical machine), consultation on experimental design, sample handling, and staining protocols, education on basic principles of flow cytometry through seminars, lab meeting sand course work.

    Scientific Director: James Crowe, MD
    Managing Director: Kevin Weller
    Faculty Advisory Committee Members:
    Mark Boothby (Pathology, Microbiology & Immunology)
    Alyssa Hasty (Molecular Physiology & Biophysics)
    Scott Hiebert (Cancer Center)
    David Miller (Cell and Developmental Biology)
    Richard Peek (Digestive Disease Research Center)
    Eric Sebzda (Pathology, Microbiology & Immunology)
    Michelle Southard-Smith (Genetic Medicine)

  • VUMC Health Services Research Cores


    Database Analysis Core
    Offers education, consultation, and programming support on capabilities, access, and appropriate use of large publicly available health-related datasets for the purposes of developing hypotheses for health research, guiding policy choices, or documenting community health concerns. Contact:

    Human Factors and Systems Safety Core
    Provides training and assistance in observing and analyzing human factors involved in both individual clinical tasks and complex health systems in order to improve patient safety and provider and system efficiency in health care delivery.

    Qualitative Research Core
    Offers consultative services, equipment, and facilitation to support investigators planning to conduct qualitative studies, with a particular focus on use of structured and semi-structured interviews, web-based collection of qualitative data, direct observation of behavior, and focus groups. Contact:


    Meharry-Vanderbilt Community Engaged Research Core (CERC)
    Offers consultation, infrastructure and support services to facilitate community engagement in clinical and translational research. Services include consultations with faculty experienced in community engaged methods of research, Community Review Boards, training on community engagement strategies, and connections to potential community partners. CERC is also working to develop a middle Tennessee practice-based research network. Contact:

    Effective Health Communication Core
    Provides consultation on aspects of research study design, informed consent, patient recruitment, measurement, data collection, quantitative and qualitative analysis, and manuscript preparation related to health literacy, numeracy, cross-cultural communication and mobile device or internet-based communication. Contact: kathryn.m.goggins@Vanderbilt.Edu

  • VUMC Hormone Assay and Analytical Services Core

    Assists investigators in the measurement of amino acid profiles and hormones in biologic fluids as related to diabetes and endocrine and metabolic research. The core provides space, equipment, and personnel for sample analysis and method development.

    Manager: Dale Edgerton
    Phone: (615) 936-1624

  • VUMC Investigational Drug Service

    The Investigational Drug Service (IDS) is a team of specially trained pharmacists and certified pharmacy technicians within the VUMC Department of Pharmaceutical Services. The IDS team is dedicated to helping investigators accomplish research goals while maintaining compliance with all applicable standards and regulations. Study protocol dispensing can be accommodated for inpatient and outpatient studies on the main campus and at clinic sites such as One Hundred Oaks.

    Program Director: Rick Malone 
    Phone: (615) 343-5146, (615) 500-2981 

  • VUMC Molecular Cell Biology Resource Core

    This resource provides custom DNA and RNA synthesis as well as custom cell culture media at a fraction of the cost of commercial sources. The supply arm of this resource stocks freshly prepared bacteria growth plates with or without antibiotics, transformation competent bacteria, and commercial kits and reagents for molecular biology research. On-line ordering is available and there is free delivery to the lab.

    The Bioanalytics Facility houses state-of–the-art instrumentation for imaging and quantitation of fluorescent, radioactive, luminescent, and chemiluminescent signals from gels, membranes, or multiple well plates. Gels and membranes stained with visible dyes or ethidium bromide can also be analyzed. Digitized images can be saved to transportable storage for further analysis in the lab or prints can be made on site. This facility also has four "real-time" PCR instruments available on a sign-out basis.

    Manager: Kris Ellis 2-7238
    E-Mail: kris.ellis@Vanderbilt.Edu

    VUMC Center for Precision Medicine - Phenotyping and PheWAS Core

    Our core mission is to assist researchers who seek to advance the basic informatics methods, and to apply advanced methods to "understand" unstructured, and sometimes inaccurate, biomedical text and electronic medical record data. 

    For basic science applications, we provide services for natural language processing methods, terminology development, and integration of disparate data sources (such as coded and free text sources). 

    We provide three major domains of application of advanced informatics techniques: educational informatics and clinical phenotyping (deriving phenotypes from EMR records).  We pursue the latter to discover clinical knowledge, gene-disease relationships (genomics, GWAS, and PheWAS), and gene-drug-outcome relationships (pharmacogenomics).

    Core Leadership
    Center Director:
     Josh C. Denny, MD, MS
    Core Scientific Director: Lisa Bastarache

    Service Requests:

    To make a service request, please click HERE

    Contact Information

    For general questions or specific questions on a service request, please contact Janey Wang, Core Operations Manager.

  • VUMC Sleep Research Core

    The Vanderbilt Sleep Research Core offers two hard-wired sleep systems with synchronized video-polysomnography and 21 channels of EEG, with dedicated registered sleep technologists. A sleep core/sleep reading center manager and the core director (Dr. Beth Malow) assist investigators with protocol development. It offers polysomnography, titrations with continuous positive airway pressure, multiple sleep latency testing, and wrist actigraphy (wireless devices that measure sleep-wake patterns non-intrusively based on accelerometers that measure activity vs. rest). The core provides for centralized scoring of polysomnography and actigraphy data for multicenter trials. In addition to the scoring component, emphasis is placed on the quality of the sleep recordings at the individual sites with close communication among the individual site technologists and the sleep core manager.

    Scientific Director: Beth Malow
    Manager: Melissa Francis
    E-Mail: melissa.francis@Vanderbilt.Edu

  • VUMC Translational Pathology Shared Resource

    The Translational Pathology Shared Resource will advance biomedical research and personalized medicine by providing Vanderbilt Investigators:

    - Access to consented and de-identified human tissue specimens

    -Comprehensive, state of the art diagnostic, necropsy and comparative pathology services for animal model systems with specific expertise and focus on mouse models

    -Research histology including advanced techniques, immunohistochemistry, laser capture micro-dissection and tissue micro-array preparation

    -Access to experts in veterinary and human pathology


    Associate Director: Kelli Boyd
    Phone: (615) 322-3596

    TPSR Contact: Sherry Smith
    Phone: (615) 322-3667

  • VUMC VANTAGE: Vanderbilt Technologies for Advanced Genomics

    VANTAGE is a genomics core laboratory consolidation initiated by an $8.6 million ARRA funded NIH grant award to Vanderbilt University Medical Center, with an overall goal of creating a new collaborative [VANTAGE] shared resource that accelerates discovery in genome sciences and personalized medicine, providing state-of-the art research shared resource facilities and technology.

    The NIH grant provided funds for complete modernization of 12,505 Net Square Feet of aging laboratory space in Medical Center North, and for new cutting edge scientific equipment now utilized by the core labs located in the newly renovated space. Renovation was completed in May 2012, and the core labs (see below) are now in full service mode in their new laboratories.

    VANTAGE is a one-stop genomics research resource, including: Illumina genotyping, DNA extraction and banking, Affymetrix–based genotyping and expression microarrays, Sanger sequencing and Next Generation Sequencing (NGS) among many other specialized services. These activities are now part of an overall structure that takes full advantage of their new physical co-location together with the Flow Cytometry Shared Resource in VANTAGE.

    Center for Technology Transfer and Commercialization toured VANTAGE as part of DNA Day celebration: Watch the video.VANTAGE recently achieved LEED Gold certification: Read More.

    VANTAGE Scientific Director: James Crowe, M.D.
    E-Mail: james.crowe@Vanderbilt.Edu

    Associate Director, Immunogenetics: Simon Mallal, MBBS

    VANTAGE Associate Director: Thomas Stricker, M.D., Ph.D.
    E-Mail: thomas.stricker@Vanderbilt.Edu

    Biobanking Services and Low-Throughput Genotyping Manager: Cara Sutcliffe
    Phone: (615) 936-2744

    Sequencing, High-Throughput Genotyping and Expression Services Liaison: Lana Olson
    Phone: (615) 936-3815


    Faculty Advisory Committee Members (2014-2015):
    Jim Crowe
    Simon Mallal
    Yu Shyr
    Wei Zheng
    Dan Roden
    David Miller
    Sam Santoro
    Roger Cone
    Scott Hiebert
    David Haas
    David Calkins
    Al Powers
    Eric Skaar

  • VUMC VANGARD: Vanderbilt Technologies for Advanced Genomics Analysis and Research Design

    VANGARD was launched Nov 1, 2012 to help investigators design experiments and analyze and interpret data generated by VANTAGE. The mission of the core is to consolidate the genomics data pipeline across the university and allow investigators to leverage the opportunities provided by next-generation sequencing and other genomics technologies. VANGARD operates in conjunction with VANTAGE, providing experimental design, quality assessment of data, analysis and results interpretation, and data storage to investigators, while VANTAGE provides technical services with a focus on next-generation sequencing including DNA-seq and RNA-seq. VANGARD also provides biostatistical and bioinformatics support for all genomic experiments that utilize BioVU specimens. For small-scale projects, VANGARD uses a fee-for-service model which includes basic experimental design and quantitative analysis for genomic data generated by VANTAGE as well as data storage and backup. Large-scale projects and those that require more complex and detailed analysis may be handled collaboratively.

    For general questions or to request VANGARD services, please contact

    VANGARD Leadership Team:
    Director: Yu Shyr, Ph.D.

    Technical Director for Bioinformatics:
    Yan Guo, Ph.D.

    Technical Director for Informatics:
    Lynne Berry, Ph.D.

    VANGARD Core Facility Manager:
    Lana Olson

  • VUMC VUIIS - Vanderbilt University Institute of Imaging Science

    VUIIS supports advances in physics, engineering, computing and other clinical and basic sciences for the development and application of new and enhanced imaging techniques to address problems in biology and medicine, in health and disease. Faculty and trainees pursue research in developing new imaging methods and techniques, as well as in diverse applications. The addition of a 7 tesla magnet, one of only about eight in the United States, has enabled researchers to generate images down to the molecular level and will ensure Vanderbilt remains at the forefront of research in magnetic imaging.

    Some of the core areas of current interest are the development of methods for the assessment of structure, function, and metabolism including imaging in broad areas such as cancer, brain physiology, transgenic mice, cellular and molecular as well as research into the physics of imaging and spectrometry. The Institute also provides an exemplary training environment for postdoctoral fellow, graduate and medical students and undergraduates.

    Center Director: John Gore

    Center for Human Imaging
    Scientific Director: Seth Smith
    Phone: (615) 322-6211
    Manager: Brian Welch
    Phone: (615) 343-7754

    Center for Small Animal Imaging
    Center Director: John Gore
    Scientific Director: Mark Does
    Manager: Jarrod True

    Center for Molecular Probes – Radiochemistry
    Scientific Director: Charles Manning
    Technical Director: Mike Nickels


  • VUMC Zebrafish Aquatic Facility

    The current zebrafish facility is composed of approximately 100 research tanks available for short and long-term studies, and a significant expansion project is underway. The facility enables investigator access to the unique advantages of the zebrafish model, which provides hundreds of mutant and transgenic zebrafish with unique properties suited for specific experiments. This core’s essential mission is to provide a reliable mechanism for incorporation and propagation of new and existing zebrafish lines into the core.

    Scientific Director: Ela Knapik
    E-Mail: ela.knapik@Vanderbilt.Edu
    Phone: (615) 322-7569


    Other VUMC Shared Resources