Overview
The Crowe laboratory studies the molecular
basis for neutralization of viruses by antibodies. The group is developing
hybrid methods combining laboratory and computational methods to study and
predict the activity of protein at the nanoscale.
Unraveling the Mystery of Immunity | James Crowe | TEDxNashville
Awards
-Elected Member, National Academy of Medicine
-Elected Member, National Academy of Inventors
-Samuel Rosenthal Prize for Excellence in Academic Pediatrics, Samuel Rosenthal Foundation
-Stanley J. Korsmeyer Award, American Society for Clinical Investigation
-Distinguished Medical Alumnus Award, UNC School of Medicine, Chapel Hill, NC
-Best Academic Research Team, 11th Annual Vaccine Industry Excellence Awards, World Vaccine Congress
-Future Insight Prize; Merck KGaA; 1 million Euro scientific prize for Pandemic Protection, shared with Pardis Sabeti, 2019
-10 Superheroes Fighting COVID-19, MediFind, 2020
-Golden Goose Award, American Association for the Advancement of Science “For scientific contributions with great societal benefit” 2021
-Southeastern Conference Faculty Achievement Award. 2021
-Founders Award, Project C.U.R.E. Nashville, 2021
-Expertscape Expert in Human Influenza (top 1% of scholars writing about human influenza over the past 10 years, 2021
-Highly Cited Researcher, Clarivate™ (researchers who produced top 1% paper by citations), 2021
-The Harrington Prize for Innovation in Medicine, Harrington Discovery Institute and the American Society for Clinical Investigation, awarded to an inventive physician-scientist who has helped move science forward with novel research that has potential for clinical application. Shared with Michel Nussenzweig, 2022
-R&D100 award and a R&D100 Gold Medal for a COVID-19 special recognition category from the R&D100 Awards (“Oscars of Innovation”), San Diego, CA, 2022
-Highly Cited Researcher, Clarivate™ (researchers who produced top 1% paper by citations), 2022
-TIME, The Best Innovations of 2022. For tixagevimab and cilgavimab antibodies for COVID-19, 2022
-Building the Foundation Award 2023, Research!America, recognizes one or more individuals whose basic research discoveries have played a pivotal role in advancing public health, 2023
-Distinguished Alumnus Award, Davidson College. The John W. Kuykendall Award for Community Service, 2023
-Award for Distinguished Research in the Biomedical Sciences, Association of American Medical Colleges, 2023
-Award for Applied and Biotechnological Research, American Society for Microbiology, 2024
-Mentor of the Year Award, Vanderbilt Postdoctoral Association
-Norman J. Siegel New Member Outstanding Science Award, American Pediatric Society
-Chancellor's Research Award, Vanderbilt University
-Ernest W. Goodpasture Faculty Research Award, Vanderbilt University Medical Center
-F. Peter Guengerich Award for Mentoring Postdoctoral Fellows, Vanderbilt University Medical Center
-Outstanding Investigator Award, American Federation for Medical Research
-E. Mead Johnson Award for Excellence in Pediatric Research, Society for Pediatric Research
-Oswald Avery Award for Early Achievement, Infectious Diseases Society of America
-Teacher of the Year Award, Vanderbilt University School of Medicine Interdisciplinary Graduate Program
-Judson Daland Prize for Outstanding Achievement in Patient-Oriented Clinical Research, American Philosophical Society, Philadelphia, PA
-Young Investigator Award, Society for Pediatric Research
-Young Investigator Award, Pediatric Infectious Diseases Society
-Turner Scholar Award, Vanderbilt University
-Dade MicroScan Young Investigator Award, American Society for Microbiology
-Basil O’Connor Scholar Research Award, March of Dimes
Selected Publications
An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies. VanBlargan LA, Errico JM, Halfmann PJ, Zost SJ, Crowe JE, Purcell LA, Kawaoka Y,Corti D, Fremont DH, Diamond MS, Nature Medicine, 28, 490, (2022) View Abstract
Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan XY, Torres JL, Copps J, de la Peña AT, Crowe JE, Ward AB , Science Advances, 8, , (2022) View Abstract
Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T cells. Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT, ACS Nano, 13, 10939-10960, (2019) View Abstract
Education
M.D., University of North Carolina, 1987B.S., Premedicine, Davidson College, 1983