Personnel

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Frederick Haselton

Frederick R. Haselton

Professor of Biomedical Engineering
Professor of Ophthalmology and Visual Sciences
Professor of Chemistry
5932B Stevenson Center
615-322-6622
Email
Website

Overview

Much of my personal motivation for working in biomedical engineering derives from my interest in dreaming up new technologies or devices to directly impact health and our understanding of the underlying cellular and molecular phenomena. My laboratory has made contributions in many diverse areas from fluid mechanics of high frequency ventilation used with premature infants to optically activated gene expression for delivering targeted genetic therapies. Many of our current lab projects involve the application of unusual physical properties at the micro and nanoscale to develop novel diagnostic tools. I am particularly excited our recent progress in developing simple diagnostic tools based on the science underlying phenomena as diverse as the optical properties of quantum dots and the microfluidics of the coffee ring phenomenon. With further development, these technologies offer to deliver new diagnostic tools to a greater fraction of the world’s population.

Awards

-Fellow, AIMBE

Selected Publications

Addition of mirror-image L-DNA elements to DNA amplification circuits to distinguish leakage from target signal. Zimmers ZA, Adams NM, Haselton FR, Biosensors & Bioelectronics, 188, 113354, (2021) View Abstract

Controlling Droplet Marangoni Flows to Improve Microscopy-Based TB Diagnosis. Pearlman SI, Tang EM, Tao YK, Haselton FR, Diagnostics, 11, 2155, (2021) View Abstract

COVID-19 diagnostics for resource-limited settings: Evaluation of "unextracted" qRT-PCR. Adams NM, Leelawong M, Benton A, Quinn C, Haselton FR, Schmitz JE, Journal of Medical Virology, 93, 559-563, (2021) View Abstract

Recurrence monitoring for ovarian cancer using a cell phone-integrated paper device to measure the ovarian cancer biomarker HE4/CRE ratio in urine. Kight EC, Hussain I, Bowden AK, Haselton FR, Scientific Reports, 11, 21945, (2021) View Abstract