Overview
Much of my personal motivation for working in
biomedical engineering derives from my interest in dreaming up new technologies
or devices to directly impact health and our understanding of the underlying
cellular and molecular phenomena. My laboratory has made contributions in many
diverse areas from fluid mechanics of high frequency ventilation used with
premature infants to optically activated gene expression for delivering
targeted genetic therapies. Many of our current lab projects involve the application
of unusual physical properties at the micro and nanoscale to develop novel
diagnostic tools. I am particularly excited our recent progress in developing
simple diagnostic tools based on the science underlying phenomena as diverse as
the optical properties of quantum dots and the microfluidics of the coffee ring
phenomenon. With further development, these technologies offer to deliver new
diagnostic tools to a greater fraction of the world’s population.
Awards
-Fellow, AIMBE
Selected Publications
Addition of mirror-image L-DNA elements to DNA amplification circuits to distinguish leakage from target signal. Zimmers ZA, Adams NM, Haselton FR, Biosensors & Bioelectronics, 188, 113354, (2021) View Abstract
Controlling Droplet Marangoni Flows to Improve Microscopy-Based TB Diagnosis. Pearlman SI, Tang EM, Tao YK, Haselton FR, Diagnostics, 11, 2155, (2021) View Abstract
COVID-19 diagnostics for resource-limited settings: Evaluation of "unextracted" qRT-PCR. Adams NM, Leelawong M, Benton A, Quinn C, Haselton FR, Schmitz JE, Journal of Medical Virology, 93, 559-563, (2021) View Abstract
Recurrence monitoring for ovarian cancer using a cell phone-integrated paper device to measure the ovarian cancer biomarker HE4/CRE ratio in urine. Kight EC, Hussain I, Bowden AK, Haselton FR, Scientific Reports, 11, 21945, (2021) View Abstract
Education
Ph.D., Bioengineering, University of Pennsylvania, 1981PA. B.A., Mathematics, Haverford College, 1969