Current Opportunities at Vanderbilt

Potential Projects Currently Available:
1. A project to determine possible therapies using small compound inhibitors that negatively control metabolic enzymes
2. A project to determine the independent roles of oncogenes that lead to the malignant transformation of pre-cancerous cells

Relevant Publications:
1. Min J, Zhang C, Bliton RJ, Caldwell B, Caplan L, Presentation KS, Park DJ, Kong S, Washington MK, Kim W, Lau KS, Magness ST, Lee H, Yang H, Goldenring JR, Choi E. Dysplastic stem cell plasticity functions as a driving force for neoplastic transformation of pre-cancerous gastric mucosa. Gastroenterology. 2022 Jun 11;S0016-5085(22)00626-6. PMID: 35700772. 

2. Kim H, Jang B, Zhang C, Caldwell B, Park DJ, Kong SH, Lee HJ, Yang HK, Goldenring JR, Choi E. Targeting Stem Cells and Dysplastic Features with Dual MEK/ERK and STAT3 Suppression in Gastric Carcinogenesis. Gastroenterology. 2024 Jan;166(1):117-131. doi: 10.1053/j.gastro.2023.09.040. PMID: 37802423.

3. Won Y, Jang B, Lee SH, Reyzer ML, Presentation KS, Kim H, Caldwell B, Zhang C, Lee HS, Lee C, Trinh VQ, Tan MCB, Kim K, Caprioli RM, Choi E. Oncogenic fatty acid metabolism rewires energy supply chain in gastric carcinogenesis, Gastroenterology. 2024 May;166(5):772-786.e14. PMID: 38272100.

Position Available:
Postdoctoral fellow or Research instructor

Successful Candidates:
1. A PhD degree in cell/stem cell biology or cancer biology
2. Experience with transgenic mouse models
3. Experience with scRNA-seq or organoids strongly encouraged
4. A track record of original publications, with at least one first-authored scientific publication
5. Strong communication skills in English, oral and written