Current Opportunities at Vanderbilt

Receptor mediated signal transduction is a vital cellular process that is required for cell-to-cell communication and to maintain homeostasis. However, it is still poorly understood how: 1) receptors delineate between different activating stimuli (biased signaling), and 2) how they transmit those signals intracellularly to achieve different cellular outcomes (e.g. differentiation, proliferation, apoptosis, etc.). It is becoming increasingly clear that the static structural views provided by crystallography and cryo-EM cannot explain biased signaling or the effects of oncogenic mutations on receptor mediated signaling. Specifications of cellular outcomes appear to depend on precise signaling kinetics in the cell, and a dynamic view of the receptor 'in action' will be crucial for understanding this. To tackle this challenge, the Mudumbi Lab uses a number of state-of-the-art imaging based approaches that allows us to directly observe and understand the dynamics of individual receptors - at the single-molecule level - in living cells.

Outstanding postdoctoral candidates that are naturally curious and interested in studying these topics in depth and think about them critically are invited to submit their application for a postdoctoral position in the Mudumbi Lab. The ideal candidate will have a track record of scientific rigor, productivity, and creativity. Skills in image analysis, live-cell imaging, and biochemical approaches are desired but not required (we understand that you are also here to expand your scientific repertoire!), training will be provided in necessary areas. Candidates will work closely with the PI, other lab members, and collaborators to study EGFR mediated signal transduction. 

The appropriate candidate should have a Ph.D. in Biophysics, Cancer Biology, Biochemistry, Biology, or other related disciplines.

Please visit https://lab.vanderbilt.edu/mudumbi-lab/ for more details about the lab and its research interests.

Please email krishna.mudumbi@vanderbilt.edu the follow information: 
1) A cover letter that includes a description of your past research experience, your current and future research interests, and why you want to join the lab. It is also appropriate to include any project ideas, as they relate to signal transduction, that you would like to work on in the lab. 
2) CV
3) Contact information for 3 references

Review of applications will begin immediately, and the position will remain open until filled.