Written by Taseer Ahmad, Pharm. D., Ph.D.
I grew up in a village in the north of Pakistan, surrounded by beautiful mountains where we speak the language “Pushto.” Since childhood, I wanted to become a physician. So, even after putting in my best efforts, I was unable to get admission to the medical school in Pakistan. But it is important to have a plan B in life. In my case, plan B mostly works for me. So, I started my career as a pharmacist and chose Pharm.D. In my Master's studies, I studied Pharmacology as a subject of interest; this subject is shared by both Pharm.D and Medical students. Then, I tried tirelessly to get admission to one of the top 200 universities globally, but again, I revisited my Plan B and secured PhD admission in my native country. During PhD (Pharmacology) study, I was lucky to visit the Queen’s Medical Center, University of Nottingham, UK, through a short-term exchange program. The dream came true when I joined Vanderbilt University Medical Center (VUMC), one of the best Medical Schools in the US, as a postdoc research fellow.
The main objective of my career is to apply and upgrade my professional skills and experience in cardiovascular pharmacology. I want to use my scientific knowledge and communication skills to help in the development of novel therapeutics and to improve patients' lives. Before I discuss my research journey, I want to share that I taught basic Pharm.D subjects in Pharmaceutical Institutions of Pakistan to Pharm.D and Masters’ students for almost eight years. Currently, I am on study leave from the College of Pharmacy, University of Sargodha, Pakistan. So, I strived to balance both teaching and basic research in the last few years, which I also want to continue in the future.
My research area is Cardiovascular Pharmacology. For the last decade, I have been working on different techniques related to cardiovascular pathophysiology in animal models. In my early career, I worked on isolated rabbit hearts, and also learned how to measure non-invasive blood pressure using tail-cuff apparatus in animal models. Under the supervision of Dr Alamgeer, an Associate Professor in Pakistan, I learned the basic techniques in cardiovascular Pharmacology and published several articles in reputed journals. Then, I joined Prof. Dr. Abdul Jabbar Shah (Ex-Postdoc Fellow, Medical College of Wisconsin, US) laboratory in Pakistan. In Dr. Shah’s Lab I learned how to measure invasive BP in rat models, ECG analysis during myocardial infarction, and vascular reactivity in isolated rat aortic rings. In addition, during my PhD, I completed a six-month fellowship program under the supervision of Dr. Richard Roberts, Associate Professor, University of Nottingham, UK. In Dr. Richard’s lab, our study focused on the effect of some selected natural compounds on the porcine coronary artery.
After graduating in 2022, I joined Dr. Kirabo Lab as a Postdoctoral Research Fellow in December 2022, a recognised expert in salt-sensitive blood pressure and its immune-linked mechanism(s). Dr. Kirabo Lab at Vanderbilt University Medical Center (VUMC) is undoubtedly one of the best places I could ever dream of joining as a postdoctoral research fellow. My postdoc project provides me with new conceptual and technical training in cardiovascular-related disorders, particularly the role of monocytes in inflammation and salt-sensitivity of blood pressure. This will help me achieve my long-term goals to become a successful independent scientist. My training has thus far provided me with extensive basic science knowledge and technical skills and career development opportunities, including literature analysis, public speaking, responsible conduct of research, and career development. In Dr. Kirabo’s Lab I am working on multiple projects; the leading project is to study the role of Activated Protein-1 (FOS-JUN) complex in salt-sensitive blood pressure. Recently, we have published four articles in prestigious journals, and a few are under review.
In addition to my research activities, I co-chair the career development committee at Vanderbilt Postdoctoral Association (VPA). We have arranged different activities related to career development for Postdoc fellows, including a monthly Monday motivation letter and workshop on mentorship. The OPA board, along with the Vanderbilt Postdoctoral Association (VPA), are excellently keeping the postdoc community connected through the Annual VPA symposium and organising workshops. I am also a member of professional organisations such as the American Heart Association (AHA), the American Physiological Society (APS), and the European Society of Cardiology (ESC). During the last year of my stay at Vanderbilt, I was lucky to attend and present my research at the conferences organised by APS and AHA. The AHA awarded me a prestigious “Young Investigator Travel Award” to attend Hypertension Session 2023. I am also grateful to The Vascular Biology & Hypertension (VB&H), University of Alabama at Birmingham, for the “Travel Award” to attend the symposium in April 2023. I will credit my PI, Dr. Kirabo, for encouraging me and supporting me in attending these conferences, which just opened my mind to new horizons of thoughts in the field of medical research, specifically immune-mediated salt-sensitivity of blood pressure. Overall, I am grateful that I got the chance to work with all the amazing people who share a similar passion for biomedical research.
In my free time, I like to spend time with my family and friends, participate in volunteer activities, play cricket and football, hike, make tea (Chai), and cook different Pakistani-style food.