Kevin Schey
Using mass spectrometry to understand fundamental biochemical processes
![](https://cdn.vanderbilt.edu/vu-URL/wp-content/uploads/sites/212/2024/09/06130515/Head.shot_.2019-scaled-e1725645998128-843x1024.jpg)
The focus of the Schey lab is on the development and application of mass spectrometry to understand fundamental biochemical processes in health and disease. Areas of technology development include: imaging mass spectrometry, native mass spectrometry, membrane protein analysis and proteomics. Areas of application include: diseases of aging such as Alzheimer’s disease, cataract and age-related macular degeneration. State-of-the-art instrumentation and methods, such as hydrogen-deuterium exchange MS, imaging mass spectrometry, native mass spectrometry, and crosslinking mass spectrometry are employed to examine protein-protein/lipid interactions, post-translational modifications, protein crosslinking, spatially-resolved proteomics/lipidomics and cell aging.
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