CSB Research Spotlight: Ren Lab – Understanding mRNA export

Posted by daviskd2 on Thursday, December 5, 2024 in News.

A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers.

First author Bradley Clarke and coauthors describe key steps in the mRNA nuclear export pathway and explain how the cellular machinery engages with newly synthesized mRNA.

Read more about this new insight.