CSB Research Spotlight: Mchaourab Lab – Describing  conformational landscapes of cell membrane transporters

Posted by daviskd2 on Friday, December 6, 2024 in News.

PhD student Alexandra Schwartz and Professor Hassane Mchaourab (Molecular Physiology and Biophysics, Center for Applied Artificial Intelligence in Protein Dynamics) developed a methodological blueprint to describe the structure of cell membrane transporters.

Read more to learn how the Spectroscopy and AI method provide a unique window into protein structure and a mechanism of action.

Morphing of MhsT models obtained from SPEACH_AF illustrating its conformational changes: