Discovery-Based Metabolomics Lifts the Curtain on MBLAC1 Gene’s Functional Roles
A research project lead by Professor Blakely (Florida Atlantic University) in collaboration with the Center for Innovative Technology (CIT) at Vanderbilt has been investigating the physiological role of the MBLAC1 gene via global, untargeted mass spectrometry analysis. In the serum metabolome the team was able to discover unique differences in primary bile acid biosynthesis and linoleate metabolism between MBLAC1 knock-out and age-matched wild-type mice. Future targeted metabolomics studies are expected to reveal the MBLAC1 substrate and its related neuroprotective effects.
The full, peer-reviewed publication can be found here.
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allwarv2020-06-15 07:37:092020-06-08 07:45:01A Guide to Metabolite Annotation: A Mini-Series (Part II)
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allwarv2020-06-08 07:33:402020-06-08 07:34:40A Guide to Metabolite Annotation: A Mini-Series
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allwarv2020-01-14 15:07:102020-01-14 15:52:20Small Molecule Omics and Cancer Biology
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allwarv2019-07-31 08:58:202019-07-31 09:07:42The Human Microbiome’s Metabolome
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allwarv2019-04-17 12:16:102019-04-17 12:39:16Advancing Lipidomics
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allwarv2019-02-28 13:14:582019-04-17 12:41:02Liquid Handling Platform Added for Large Metabolomics Studies
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allwarv2019-02-21 14:01:192019-04-17 12:42:31Quantity of Identified Metabolites in Untargeted Experiments
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allwarv2019-01-21 13:13:222019-04-17 12:44:31Metabolic Quenching
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allwarv2019-01-21 13:12:582019-04-17 12:45:55High-Throughput Multi-Omic Analyses
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allwarv2019-01-21 13:12:392019-04-17 12:47:30Qualitative Amino Acid Panel
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