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  1. Discovery could lead to neutralizing West Nile virus

    ... University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent ...

    sommers - 02/21/2019 - 9:51am

  2. Vanderbilt vaccine pioneer James Crowe honored with major science prize

    ... Vaccine Center , will be honored today by the science and technology company Merck KGaA, Darmstadt, Germany for his contributions to ... Their research has led to patents and licensures for several neutralizing antibodies and vaccines, some of which have progressed to clinical ...

    sommers - 07/17/2019 - 11:16am

  3. Chikungunya antibody identified at VUMC moves forward

    ... islands, but which is spreading outside the tropics. The neutralizing antibody developed by Evotec, EVT894, was isolated from the blood ... basic science discoveries into medicines that can improve human health.” During the past 25 years, Crowe and his colleagues have ...

    sommers - 03/08/2021 - 8:29am

  4. Researchers developing potential Coronavirus antibody therapies

    ... in humans. “Our goal is to prepare antibodies for human clinical trials by this summer,” said  James Crowe , MD, director of ... rare antibodies with a laser-like focus for finding — and neutralizing — a specific virus. Resources at VUMC that enable the ...

    sommers - 03/26/2020 - 1:36pm

  5. Antibody isolated at VUMC found to halt dengue virus

    ... University Medical Center that “broadly neutralizes” the human dengue virus, biologists at the University of California San Diego and ... arboviruses, including Zika and chikungunya, against which neutralizing antibodies also have been developed, the researchers concluded. ...

    sommers - 01/24/2020 - 9:07am

  6. Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial

    ... as a treatment for neuropsychiatric disorders.”  Human clinical trials are a significant advancement in a five-step  drug ... collaboration was facilitated by the   Center for Technology Transfer and Commercialization . Vanderbilt researchers who ...

    sommers - 01/17/2024 - 10:08am

  7. VUMC and AstraZeneca join forces to identify potential COVID-19 treatments

    ... technologies and have already discovered SARS-CoV-2 neutralizing antibodies,” said VVC Director  James Crowe  Jr., MD. ... specific viral proteins. In the laboratory, these “monoclonal” antibodies are then comprehensively examined to identify those ... virus. Using these techniques, they have generated human monoclonal antibodies against a wide range of pathogenic viruses ...

    sommers - 04/09/2020 - 12:35pm

  8. VUMC-led team isolates antibody that blocks bird flu

    ... Microbe , James Crowe Jr., MD, and colleagues report that human monoclonal antibodies, isolated from two survivors of H7N9 infections and ... and rotavirus. They have pioneered the rational design of neutralizing antibody treatments and vaccines, some of which have progressed to ...

    sommers - 12/16/2019 - 10:57am

  9. Team isolates antibodies that neutralize GI bug norovirus

    ... Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of ... infected with norovirus. The researchers tested the neutralizing capability of the antibodies against live virus grown in a ...

    sommers - 02/21/2019 - 9:51am

  10. VUMC and IDBiologics Ally in Race to Develop Breakthrough Medicines for COVID-19

    ... team is pleased to partner with IDBiologics to race potent neutralizing human monoclonal antibodies to the clinic,” Dr. Crowe said. “The speed with ...

    sommers - 05/28/2020 - 2:55pm